Helical Wheel Projection
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Visualization of amino acids in an alpha helix viewed from the N or C terminus.
It is often useful to visualize the projection of amino acids in an alpha helix viewed from the N or C terminus. Such a view is called a helical wheel. Helical wheels often reveal how certain residues or sites of mutation are enriched on one face of a predicted helix.
Several sites have web-based software to draw helical wheels
- Raphael Zidovetzki's lab at UC-Riverside. This version allows a lot of customization of the view. Perl source code is also provided.
- modified version of the above at Texas A&M, patched to fix the view from the C-terminus and to manually override the hydrophobicity value for Valine.
- Univ. of Virginia
- CABM at Rutgers
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