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Jackson, AP, Thomas, GH, Parkhill, J and Thomson, NR (2009) Evolutionary diversification of an ancient gene family (rhs) through C-terminal displacement. BMC Genomics 10:584


Rhs genes are prominent features of bacterial genomes that have previously been implicated in genomic rearrangements in E. coli. By comparing rhs repertoires across the Enterobacteriaceae, this study provides a robust explanation of rhs diversification and evolution, and a mechanistic model of how rhs diversity is gained and lost.


PubMed PMC2935791 Online version:10.1186/1471-2164-10-584


Amino Acid Sequence; Bacterial Proteins/chemistry; Bacterial Proteins/classification; Bacterial Proteins/genetics; Biodiversity; Enterobacteriaceae/chemistry; Enterobacteriaceae/classification; Enterobacteriaceae/genetics; Evolution, Molecular; Genetic Loci; Genome, Bacterial; Phylogeny; Sequence Alignment


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