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Lescat, M, Hoede, C, Clermont, O, Garry, L, Darlu, P, Tuffery, P, Denamur, E and Picard, B (2009) aes, the gene encoding the esterase B in Escherichia coli, is a powerful phylogenetic marker of the species. BMC Microbiol. 9:273


Previous studies have established a correlation between electrophoretic polymorphism of esterase B, and virulence and phylogeny of Escherichia coli. Strains belonging to the phylogenetic group B2 are more frequently implicated in extraintestinal infections and include esterase B2 variants, whereas phylogenetic groups A, B1 and D contain less virulent strains and include esterase B1 variants. We investigated esterase B as a marker of phylogeny and/or virulence, in a thorough analysis of the esterase B-encoding gene.


PubMed PMC2805673 Online version:10.1186/1471-2180-9-273


Acetylesterase/genetics; Animals; Bacterial Typing Techniques; DNA, Bacterial/genetics; Escherichia coli/classification; Escherichia coli/enzymology; Escherichia coli/genetics; Escherichia coli/pathogenicity; Escherichia coli Infections/microbiology; Escherichia coli Proteins/genetics; Female; Genetic Complementation Test; Mice; Models, Molecular; Phylogeny; Protein Structure, Tertiary; Sequence Alignment; Sequence Analysis, DNA; Serine Endopeptidases/genetics; Virulence


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