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Phage lambda gam:On One Page

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Quickview

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Standard Name

Phage lambda gam

Gene Synonym(s)

gam, lambdap42

Product Desc.

host-nuclease inhibitor protein Gam

Product Synonyms(s)

gam, lambdap42

Function from GO

Biological Process

Knock-Out Phenotype
Regulation/Expression
Regulation/Activity
Quick Links

porteco.png

dnadisplay.png proteindisplay.png   pubmed.jpg   textpresso.jpg  

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Notes

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Gene

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Nomenclature

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See Help:Gene_nomenclature for help with entering information in the Gene Nomenclature table.

Standard name

Phage lambda gam

Mnemonic
Synonyms

gam, lambdap42

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Notes

Location(s) and DNA Sequence

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See Help:Gene_location for help entering information in the Gene Location and DNA sequence table.

Strain Map location Genome coordinates Genome browsers Sequence links

BW2952

NC_012759: 4137167..4137463
gbrowse_img.php?coord=4137167..4137463&genome=BW2952&name=NC_012759&trackset=0&width=300&.png

NC_001416

NC_001416: 33232..32816
gbrowse_img.php?coord=32816..33232&genome=bacteriophage_lambda&name=NC_001416&trackset=0&width=300&.png

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Notes

Sequence Features

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Feature Type Strain Genomic Location Evidence Reference Notes

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Notes

Alleles and Phenotypes

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Allele Nt change(s) AA change(s) Phenotype: Type Phenotype: Description Reference Availability Comments

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Notes

Genetic Interactions

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Interactor Interaction Allele Score(s) Reference(s) Accessions Notes

Notes

Genetic Resources

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Resource Resource Type Source Notes/Reference

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

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Notes

Links

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Product(s)

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Nomenclature

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Standard name

gam

Synonyms

gam, lambdap42

Product description

host-nuclease inhibitor protein Gam

EC number (for enzymes)


See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Notes

Function

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Gene Ontology See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status

GO:0032076

negative regulation of deoxyribonuclease activity

PMID:4275917

IDA: Inferred from Direct Assay

P

complete

GO:0032076

negative regulation of deoxyribonuclease activity

PMID:126236

IDA: Inferred from Direct Assay

P

complete

See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence


Notes

Localization

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Compartment Description Evidence Reference/Source Notes

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Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence
MDINTETEIK QKHSLTPFPV FLISPAFRGR YFHSYFRSSA MNAYYIQDRL EAQSWARHYQ
QLAREEKEAE LADDMEKGLP QHLFESLCID HLQRHGASKK SITRAFDDDV EFQERMAEHI
RYMVETIAHH QVDIDSEV
Length

138

Mol. Wt

16.346 kDa

pI

5.8 (calculated)

Extinction coefficient

14,440 - 14,565 (calc based on 6 Y, 1 W, and 1 C residues)

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Domains/Motifs/Modification Sites

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Type Residues Description Notes References
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Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

No results found for a best structure.

Models

View models at:

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Structure figures

See Help:Jmol in EcoliWiki

Orthorhombic form of gam, PDB 2UUZ

See Help:Jmol in EcoliWiki

Hexagonal form of gam, PDB:2UV1









Notes

See The crystal structure of lambda-Gam protein suggests a model for RecBCD inhibition[1]for orthorhombic and hexagonal form information.

Gene Product Resources

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Resource type Source Notes/Reference

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

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Notes

Links

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Expression

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Overview

This is a placeholder for a summary statement on how expression of this gene product is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.


Cellular Levels

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See Help:Cellular levels

Molecule Organism or Strain Value Units Experimental Conditions Assay used Notes Reference(s)

Notes

Transcription and Transcriptional Regulation

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See Help:Expression_transcription for help entering or editing information in this section of EcoliWiki.

Transcription unit(s)

Phage lambda Pl - t'j4

Phage lambda Pl - t'j3

Phage lambda Pl - t'j2

Phage lambda Pl - t'j1

Phage lambda Pl - ti

Phage lambda Pl - tl3

See Help:Expression_transcription for help entering or editing information in this section of EcoliWiki.

Notes

This is a placeholder for a summary statement about how transcription of this gene is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.

Translation and Regulation of Translation

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This picture shows the sequence around the N-terminus.

Notes

This is a placeholder for a summary statement about how translation of this gene product is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.

Turnover and Regulation of Turnover

Notes

This is a placeholder for a summary statement about turnover of this gene product. You can help EcoliWiki by becoming a user and writing/editing this statement.

Experimental

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Mutations Affecting Expression See Help:Expression_mutations for help entering or editing information in this section of EcoliWiki.

Allele Name Mutation Phenotype Reference

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Expression Studies See Help:Expression_studies for help entering or editing information in this section of EcoliWiki.

Type Reference Notes

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Expression Resources See Help:Expression_resources for help entering or editing information in this section of EcoliWiki.

Resource Name Resource Type Description Source Notes

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Notes

Accessions Related to Phage lambda gam Expression

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Database Accession Notes

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Notes

Links

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Evolution

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Homologs in Other Organisms

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Organism Homologs (Statistics) Comments

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Do-It-Yourself Web Tools

Notes

Families

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Database Accession Notes

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. Court, R et al. (2007) The crystal structure of lambda-Gam protein suggests a model for RecBCD inhibition. J. Mol. Biol. 371 25-33 PubMed EcoliWiki page

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