aaeB:Gene Product(s) - EcoliWiki
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aaeB:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

Standard name

AaeB

Synonyms

p-hydroxybenzoic acid efflux system component[1], B3240[2][1], AaeB[2][1], YhcP[2][1]

Product description

AaeAB Hydroxylated, Aromatic Carboxylic Acid Efflux Transport System Protein B[2][3];

Component of ; AaeAB Hydroxylated, Aromatic Carboxylic Acid Efflux Transport System[3]

EC number (for enzymes)
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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

QualifierGO IDGO term nameReference(s)Evidence Codewith/fromAspectNotesStatus
GO:0006810

transport

GO_REF:0000004
GO_REF:0000020

IEA: Inferred from Electronic Annotation

SP_KW:KW-0813
HAMAP:MF_01545

P

Seeded from EcoCyc 12.5 [4]

complete

GO:0016020

membrane

GO_REF:0000004
GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0397
SP_KW:KW-0472

C

Seeded from EcoCyc 12.5 [4]

complete

GO:0016021

integral to membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0812

C

Seeded from EcoCyc 12.5 [4]

complete

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Interactions

Partner TypePartnerNotesReferences

Protein

Subunits of AaeAB Hydroxylated, Aromatic Carboxylic Acid Efflux Transport System

could be indirect


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Notes

Localization

CompartmentDescriptionEvidenceNotes

plasma membrane

C-terminus localized in the cytoplasm with 10 predicted transmembrane domains

Daley et al. (2005) [5]/>


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Notes

Structure and Physical Properties

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Physical Properties

Sequence

at EcoCyc

MGIFSIANQH IRFAVKLATA IVLALFVGFH FQLETPRWAV LTAAIVAAGT AFAAGGEPYS
GAIRYRGFLR IIGTFIGCIA GLVIIIAMIR APLLMILVCC IWAGFCTWIS SLVRIENSYA
WGLAGYTALI IVITIQPEPL LTPQFAVERC SEIVIGIVCA IMADLLFSPR SIKQEVDREL
ESLLVAQYQL MQLCIKHGDG EVVDKAWGDL VRRTTALQGM RSNLNMESSR WARANRRLKA
INTLSLTLIT QSCETYLIQN TRPELITDTF REFFDTPVET AQDVHKQLKR LRRVIAWTGE
RETPVTIYSW VAAATRYQLL KRGVISNTKI NATEEEILQG EPEVKVESAE RHHAMVNFWR
TTLSCILGTL FWLWTGWTSG SGAMVMIAVV TSLAMRLPNP RMVAIDFIYG TLAALPLGLL
YFLVIIPNTQ QSMLLLCISL AVLGFFLGIE VQKRRLGSMG ALASTINIIV LDNPMTFHFS
QFLDSALGQI VGCVLAFTVI LLVRDKSRDR TGRVLLNQFV SAAVSAMTTN VARRKENHLP
ALYQQLFLLM NKFPGDLPKF RLALTMIIAH QRLRDAPIPV NEDLSAFHRQ MRRTADHVIS
ARSDDKRRRY FGQLLEELEI YQEKLRIWQA PPQVTEPVNR LAGMLHKYQH ALTDS
Mol. Wt

73.59 kDa (calc) [2]

pI
Extinction coefficient

92360 - 93735 (calc based on 14 Y, 13 W, and 11 C residues)

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Domains/Motifs/Modification Sites

TypeResiduesDescriptionNotes

Domain

481 - 503

Predicted membrane-spanning helix.

TMD predicted by TMHMM[6]' />

Domain

403 - 425

Predicted membrane-spanning helix.

TMD predicted by TMHMM[6]' />

Domain

432 - 449

Predicted membrane-spanning helix.

TMD predicted by TMHMM[6]' />

Domain

366 - 388

Predicted membrane-spanning helix.

TMD predicted by TMHMM[6]' />

Domain

151 - 168

Predicted membrane-spanning helix.

TMD predicted by TMHMM[6]' />

Domain

119 - 136

Predicted membrane-spanning helix.

TMD predicted by TMHMM[6]' />

Domain

67 - 89

Predicted membrane-spanning helix.

TMD predicted by TMHMM[6]' />

Domain

93 - 112

Predicted membrane-spanning helix.

TMD predicted by TMHMM[6]' />

Domain

38 - 60

Predicted membrane-spanning helix.

TMD predicted by TMHMM[6]' />

Domain

13 - 33

Predicted membrane-spanning helix.

TMD predicted by TMHMM[6]' />

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tmhmm.php?gene=aaeB&show=pic&.jpg
Click the image to view raw output from TMHMM.

Structure

Structures
  • No results found.
Models

View models at:

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Notes

Gene Product Resources

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Resource typeSourceNotes/Reference
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Notes

Accessions in Other Databases

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DatabaseAccessionNotes

EcoCyc (EcoliWiki Page)

EcoCyc:G7685-MONOMER

UniProt (EcoliWiki Page)

UniProt:P46481

PFAM (EcoliWiki Page)

PFAM:PF04632

RefSeq (EcoliWiki Page)

RefSeq:NP_417707


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Notes

Links

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NameURLComments
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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 4.2 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  5. Daley DO et al. (2005) Global topology analysis of the Escherichia coli inner membrane proteome. Science 308: 1321-3 PubMed EcoliWiki page
  6. 6.0 6.1 6.2 6.3 6.4 6.5 6.6 6.7 6.8 6.9 Krogh A et al. (2001) Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes. J Mol Biol 305: 567-80 PubMed EcoliWiki page


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