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aceF:Gene Product(s)
From EcoliWiki
| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| Nomenclature | Function | Interactions | Localization | Sequence | Domains | Structure | Resources | Accessions | Links | References | Suggestions |
Nomenclature
| Standard name |
AceF |
|---|---|
| Synonyms |
pyruvate dehydrogenase, dihydrolipoyltransacetylase component E2[1], B0115[2][1] |
| Product description | |
| EC number (for enzymes) | |
| edit table |
See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.
Notes
Function
Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.
| Qualifier | GO ID | GO term name | Reference(s) | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004742 |
dihydrolipoyllysine-residue acetyltransferase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0045254 |
pyruvate dehydrogenase complex |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0031405 |
lipoic acid binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0005515 |
protein binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0006096 |
glycolysis |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0008152 |
metabolic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0008415 |
acyltransferase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0016740 |
transferase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0005515 |
protein binding |
IPI: Inferred from Physical Interaction |
F |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0005515 |
protein binding |
IPI: Inferred from Physical Interaction |
F |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0005515 |
protein binding |
IPI: Inferred from Physical Interaction |
F |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0005515 |
protein binding |
IPI: Inferred from Physical Interaction |
F |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0005515 |
protein binding |
IPI: Inferred from Physical Interaction |
F |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0005515 |
protein binding |
IPI: Inferred from Physical Interaction |
F |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0005515 |
protein binding |
IPI: Inferred from Physical Interaction |
F |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0005515 |
protein binding |
IPI: Inferred from Physical Interaction |
F |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0005737 |
cytoplasm |
IDA: Inferred from Direct Assay |
C |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0016052 |
carbohydrate catabolic process |
P |
Seeded from EcoCyc 11.1[3]. |
required fields missing | ||||
| GO:0006086 |
acetyl-CoA biosynthetic process from pyruvate |
P |
Seeded from EcoCyc 11.1[3]. |
required fields missing | ||||
| GO:0009436 |
glyoxylate catabolic process |
P |
Seeded from EcoCyc 11.1[3]. |
required fields missing | ||||
| GO:0009061 |
anaerobic respiration |
P |
Seeded from EcoCyc 11.1[3]. |
required fields missing | ||||
| edit table |
Interactions
| Partner Type | Partner | Notes | References |
|---|---|---|---|
| edit table |
See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.
Notes
Localization
| Compartment | Description | Evidence | Notes |
|---|---|---|---|
| edit table |
See Help:Product_localization for how to add or edit information in this section of EcoliWiki.
Notes
Structure and Physical Properties
Physical Properties
| Sequence |
MAIEIKVPDI GADEVEITEI LVKVGDKVEA EQSLITVEGD KASMEVPSPQ AGIVKEIKVS VGDKTQTGAL IMIFDSADGA ADAAPAQAEE KKEAAPAAAP AAAAAKDVNV PDIGSDEVEV TEILVKVGDK VEAEQSLITV EGDKASMEVP APFAGTVKEI KVNVGDKVST GSLIMVFEVA GEAGAAAPAA KQEAAPAAAP APAAGVKEVN VPDIGGDEVE VTEVMVKVGD KVAAEQSLIT VEGDKASMEV PAPFAGVVKE LKVNVGDKVK TGSLIMIFEV EGAAPAAAPA KQEAAAPAPA AKAEAPAAAP AAKAEGKSEF AENDAYVHAT PLIRRLAREF GVNLAKVKGT GRKGRILRED VQAYVKEAIK RAEAAPAATG GGIPGMLPWP KVDFSKFGEI EEVELGRIQK ISGANLSRNW VMIPHVTHFD KTDITELEAF RKQQNEEAAK RKLDVKITPV VFIMKAVAAA LEQMPRFNSS LSEDGQRLTL KKYINIGVAV DTPNGLVVPV FKDVNKKGII ELSRELMTIS KKARDGKLTA GEMQGGCFTI SSIGGLGTTH FAPIVNAPEV AILGVSKSAM EPVWNGKEFV PRLMLPISLS FDHRVIDGAD GARFITIINN TLSDIRRLVM |
|---|---|
| Mol. Wt |
66.1 kDa (calc) [2] |
| pI | |
| Extinction coefficient |
20970 - 21095 (calc based on 3 Y, 3 W, and 1 C residues) |
| edit table |
See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.
Domains/Motifs/Modification Sites
| Type | Residues | Description | Notes |
|---|---|---|---|
|
Domain |
2 - 74 |
Lipoyl-binding 1 | |
|
Domain |
106 - 177 |
Lipoyl-binding 2 | |
|
Domain |
207 - 278 |
Lipoyl-binding 3 | |
| edit table |
See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.
Structure
| Structures |
|
|---|---|
| Models |
View models at: |
| edit table |
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.
Notes
Gene Product Resources
| Resource type | Source | Notes/Reference |
|---|---|---|
| edit table |
See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.
Notes
Accessions in Other Databases
| Database | Accession | Notes |
|---|---|---|
|
| ||
| edit table |
See Help:Product_accessions for help entering or editing information in this section of EcoliWiki.
Notes
Links
| Name | URL | Comments |
|---|---|---|
| edit table |
See Help:Links_table for how to enter or edit information in this section of EcoliWiki.
References
See Help:References for how to manage references in EcoliWiki.
- ↑ 1.0 1.1 1.2 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.00 4.01 4.02 4.03 4.04 4.05 4.06 4.07 4.08 4.09 4.10 4.11 4.12 4.13 4.14 4.15 4.16 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 5.0 5.1 5.2 5.3 5.4 5.5 5.6 5.7 Butland G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433: 531-7 PubMed EcoliWiki page
- ↑ Lasserre JP et al. (2006) A complexomic study of Escherichia coli using two-dimensional blue native/SDS polyacrylamide gel electrophoresis. Electrophoresis 27: 3306-21 PubMed EcoliWiki page
Categories
Categories: GO:0004742 ! dihydrolipoyllysine-residue acetyltransferase activity | GO:0045254 ! pyruvate dehydrogenase complex | GO:0031405 ! lipoic acid binding | GO:0005515 ! protein binding | GO:0006096 ! glycolysis | GO:0008152 ! metabolic process | GO:0008415 ! acyltransferase activity | GO:0016740 ! transferase activity | GO:0005737 ! cytoplasm | GO:0016052 ! carbohydrate catabolic process | GO:0006086 ! acetyl-CoA biosynthetic process from pyruvate | GO:0009436 ! glyoxylate catabolic process | GO:0009061 ! anaerobic respiration | Proteins
