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References Suggestions

Standard Name


Gene Synonym(s)

ECK3253, b3266, JW3234, envD[1], envD

Product Desc.


Component of AcrEF-TolC Multidrug Efflux Transport System[3]

AcrEF-TolC efflux pump, multidrug/solvent resistance; osmotically remedial envelope defect[4]

Product Synonyms(s)

multidrug efflux system protein[1], B3266[2][1], EnvD[2][1], AcrF[2][1] , ECK3253, envD, JW3234, b3266

Function from GO
Knock-Out Phenotype

transcription unit(s): acrEF[2]

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AcrEF confers resistance to nalidixic acid, acriflavin, indole and solvents. May have role in cell division. acrF is an acrB paralog. RND family transporter.[4]


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  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.