actP:Gene Product(s) - EcoliWiki
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actP:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

Standard name

ActP

Synonyms

acetate transporter[1], B4067[2][1], YjcG[2][1], ActP[2][1]

Product description

YjcG SSS transporter[2][3]

EC number (for enzymes)
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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

QualifierGO IDGO term nameReference(s)Evidence Codewith/fromAspectNotesStatus
GO:0016021

integral to membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0812

C

Seeded from EcoCyc 12.5 [4]

complete

GO:0031402

sodium ion binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0915

F

Seeded from EcoCyc 12.5 [4]

complete

GO:0016020

membrane

GO_REF:0000002
GO_REF:0000004
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR001734
SP_KW:KW-0397
SP_KW:KW-0472

C

Seeded from EcoCyc 12.5 [4]

complete

GO:0015293

symporter activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0769

F

Seeded from EcoCyc 12.5 [4]

complete

GO:0015123

acetate transmembrane transporter activity

GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_01426

F

Seeded from EcoCyc 12.5 [4]

complete

GO:0006814

sodium ion transport

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0739

P

Seeded from EcoCyc 12.5 [4]

complete

GO:0006811

ion transport

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0406

P

Seeded from EcoCyc 12.5 [4]

complete

GO:0006810

transport

GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR001734
SP_KW:KW-0813

P

Seeded from EcoCyc 12.5 [4]

complete

GO:0005215

transporter activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001734

F

Seeded from EcoCyc 12.5 [4]

complete

GO:0015292

uniporter activity

F

Seeded from EcoCyc 11.1[3].

required fields missing

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Interactions

Partner TypePartnerNotesReferences
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Notes

Localization

CompartmentDescriptionEvidenceNotes

plasma membrane

C-terminus localized in the cytoplasm with 13 predicted transmembrane domains

Daley et al. (2005) [5]/>

plasma membrane

From EcoCyc[3]

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Notes

Structure and Physical Properties

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Physical Properties

Sequence

at EcoCyc

MKRVLTALAA TLPFAANAAD AISGAVERQP TNWQAIIMFL IFVVFTLGIT YWASKRVRSR
SDYYTAGGNI TGFQNGLAIA GDYMSAASFL GISALVFTSG YDGLIYSLGF LVGWPIILFL
IAERLRNLGR YTFADVASYR LKQGPIRILS ACGSLVVVAL YLIAQMVGAG KLIELLFGLN
YHIAVVLVGV LMMMYVLFGG MLATTWVQII KAVLLLFGAS FMAFMVMKHV GFSFNNLFSE
AMAVHPKGVD IMKPGGLVKD PISALSLGLG LMFGTAGLPH ILMRFFTVSD AREARKSVFY
ATGFMGYFYI LTFIIGFGAI MLVGANPEYK DAAGHLIGGN NMAAVHLANA VGGNLFLGFI
SAVAFATILA VVAGLTLAGA SAVSHDLYAN VFKKGATERE ELRVSKITVL ILGVIAIILG
VLFENQNIAF MVGLAFAIAA SCNFPIILLS MYWSKLTTRG AMMGGWLGLI TAVVLMILGP
TIWVQILGHE KAIFPYEYPA LFSITVAFLG IWFFSATDNS AEGARERELF RAQFIRSQTG
FGVEQGRAH
Mol. Wt

59.2 kDa (calc) [2]

pI
Extinction coefficient

72310 - 72560 (calc based on 19 Y, 8 W, and 2 C residues)

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Domains/Motifs/Modification Sites

TypeResiduesDescriptionNotes

Domain

183 - 205

Predicted membrane-spanning helix.

TMD predicted by TMHMM[6]' />

Domain

212 - 234

Predicted membrane-spanning helix.

TMD predicted by TMHMM[6]' />

Domain

261 - 283

Predicted membrane-spanning helix.

TMD predicted by TMHMM[6]' />

Domain

303 - 325

Predicted membrane-spanning helix.

TMD predicted by TMHMM[6]' />

Domain

359 - 381

Predicted membrane-spanning helix.

TMD predicted by TMHMM[6]' />

Domain

402 - 424

Predicted membrane-spanning helix.

TMD predicted by TMHMM[6]' />

Domain

428 - 450

Predicted membrane-spanning helix.

TMD predicted by TMHMM[6]' />

Domain

462 - 484

Predicted membrane-spanning helix.

TMD predicted by TMHMM[6]' />

Domain

494 - 516

Predicted membrane-spanning helix.

TMD predicted by TMHMM[6]' />

Domain

146 - 168

Predicted membrane-spanning helix.

TMD predicted by TMHMM[6]' />

Domain

76 - 98

Predicted membrane-spanning helix.

TMD predicted by TMHMM[6]' />

Domain

103 - 125

Predicted membrane-spanning helix.

TMD predicted by TMHMM[6]' />

Domain

33 - 55

Predicted membrane-spanning helix.

TMD predicted by TMHMM[6]' />

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tmhmm.php?gene=actP&show=pic&.jpg
Click the image to view raw output from TMHMM.

Structure

Structures
  • Representative homolog:
    3DH4|A (Vibrio parahaemolyticus)
    18-430 of 549 residues (E-value: 6.3e-13) (Percent Identity: 20.00)
  • View all other structures.
Models

View models at:

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Notes

Gene Product Resources

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Resource typeSourceNotes/Reference
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Notes

Accessions in Other Databases

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DatabaseAccessionNotes

EcoCyc (EcoliWiki Page)

EcoCyc:YJCG-MONOMER

UniProt (EcoliWiki Page)

UniProt:P32705

PFAM (EcoliWiki Page)

PFAM:PF00474

RefSeq (EcoliWiki Page)

RefSeq:NP_418491


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Notes

Links

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NameURLComments
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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 3.2 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 4.2 4.3 4.4 4.5 4.6 4.7 4.8 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  5. Daley DO et al. (2005) Global topology analysis of the Escherichia coli inner membrane proteome. Science 308: 1321-3 PubMed EcoliWiki page
  6. 6.00 6.01 6.02 6.03 6.04 6.05 6.06 6.07 6.08 6.09 6.10 6.11 6.12 Krogh A et al. (2001) Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes. J Mol Biol 305: 567-80 PubMed EcoliWiki page


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