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adk:Gene Product(s)
From EcoliWiki
| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| Nomenclature | Function | Interactions | Localization | Sequence | Domains | Structure | Resources | Accessions | Links | References | Suggestions |
Nomenclature
| Standard name |
Adk |
|---|---|
| Synonyms |
adenylate kinase[1], B0474[2][1], PlsA[2][1], DnaW[2][1], Adk[2][1] |
| Product description | |
| EC number (for enzymes) | |
| edit table |
See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.
Notes
Function
Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.
| Qualifier | GO ID | GO term name | Reference(s) | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000166 |
nucleotide binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0004017 |
adenylate kinase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0005524 |
ATP binding |
GO_REF:0000002 |
IEA: Inferred from Electronic Annotation |
InterPro:IPR000850 |
F |
Seeded from EcoCyc 12.5 [4] |
complete | |
| GO:0005737 |
cytoplasm |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0006139 |
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0009165 |
nucleotide biosynthetic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0016301 |
kinase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0016740 |
transferase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0016776 |
phosphotransferase activity, phosphate group as acceptor |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0019201 |
nucleotide kinase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0019205 |
nucleobase, nucleoside, nucleotide kinase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0004017 |
adenylate kinase activity |
IDA: Inferred from Direct Assay |
F |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0005515 |
protein binding |
IPI: Inferred from Physical Interaction |
F |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0005515 |
protein binding |
IPI: Inferred from Physical Interaction |
F |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0005515 |
protein binding |
IPI: Inferred from Physical Interaction |
F |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0005524 |
ATP binding |
IDA: Inferred from Direct Assay |
F |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0009152 |
purine ribonucleotide biosynthetic process |
IMP: Inferred from Mutant Phenotype |
P |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0015951 |
purine ribonucleotide interconversion |
IMP: Inferred from Mutant Phenotype |
P |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0016208 |
AMP binding |
IDA: Inferred from Direct Assay |
F |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0015949 |
nucleobase, nucleoside and nucleotide interconversion |
P |
Seeded from EcoCyc 11.1[3]. |
required fields missing | ||||
| edit table |
Interactions
| Partner Type | Partner | Notes | References |
|---|---|---|---|
| edit table |
See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.
Notes
Localization
| Compartment | Description | Evidence | Notes |
|---|---|---|---|
|
cytoplasm |
From EcoCyc[3] | ||
| edit table |
See Help:Product_localization for how to add or edit information in this section of EcoliWiki.
Notes
Structure and Physical Properties
Physical Properties
| Sequence |
MRIILLGAPG AGKGTQAQFI MEKYGIPQIS TGDMLRAAVK SGSELGKQAK DIMDAGKLVT DELVIALVKE RIAQEDCRNG FLLDGFPRTI PQADAMKEAG INVDYVLEFD VPDELIVDRI VGRRVHAPSG RVYHVKFNPP KVEGKDDVTG EELTTRKDDQ EETVRKRLVE YHQMTAPLIG YYSKEAEAGN TKYAKVDGTK PVAEVRADLE KILG |
|---|---|
| Mol. Wt |
23.59 kDa (calc) [2] |
| pI |
5.81[2] |
| Extinction coefficient |
10430 - 10555 (calc based on 7 Y, 0 W, and 1 C residues) |
| edit table |
See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.
Domains/Motifs/Modification Sites
| Type | Residues | Description | Notes |
|---|---|---|---|
| edit table |
See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.
Structure
| Structures |
|
|---|---|
| Models |
View models at: |
| edit table |
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.
Notes
Gene Product Resources
| Resource type | Source | Notes/Reference |
|---|---|---|
| edit table |
See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.
Notes
Accessions in Other Databases
| Database | Accession | Notes |
|---|---|---|
|
| ||
| edit table |
See Help:Product_accessions for help entering or editing information in this section of EcoliWiki.
Notes
Links
| Name | URL | Comments |
|---|---|---|
| edit table |
See Help:Links_table for how to enter or edit information in this section of EcoliWiki.
References
See Help:References for how to manage references in EcoliWiki.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 3.2 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.00 4.01 4.02 4.03 4.04 4.05 4.06 4.07 4.08 4.09 4.10 4.11 4.12 4.13 4.14 4.15 4.16 4.17 4.18 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ Bârzu O & Michelson S (1983) Simple and fast purification of Escherichia coli adenylate kinase. FEBS Lett 153: 280-4 PubMed EcoliWiki page
- ↑ Ishige K & Noguchi T (2000) Inorganic polyphosphate kinase and adenylate kinase participate in the polyphosphate:AMP phosphotransferase activity of Escherichia coli. Proc Natl Acad Sci U S A 97: 14168-71 PubMed EcoliWiki page
- ↑ 7.0 7.1 Butland G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433: 531-7 PubMed EcoliWiki page
- ↑ 8.0 8.1 Lin Y & Nageswara Rao BD (2000) Structural characterization of adenine nucleotides bound to Escherichia coli adenylate kinase. 2. 31P and 13C relaxation measurements in the presence of cobalt(II) and manganese(II). Biochemistry 39: 3647-55 PubMed EcoliWiki page
- ↑ 9.0 9.1 Glaser M et al. (1975) Role of adenylate kinase in the regulation of macromolecular biosynthesis in a putative mutant of Escherichia coli defective in membrane phospholipid biosynthesis. J Bacteriol 123: 128-36 PubMed EcoliWiki page
Categories
Categories: GO:0000166 ! nucleotide binding | GO:0004017 ! adenylate kinase activity | GO:0005524 ! ATP binding | GO:0005737 ! cytoplasm | GO:0006139 ! nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | GO:0009165 ! nucleotide biosynthetic process | GO:0016301 ! kinase activity | GO:0016740 ! transferase activity | GO:0016776 ! phosphotransferase activity, phosphate group as acceptor | GO:0019201 ! nucleotide kinase activity | GO:0019205 ! nucleobase, nucleoside, nucleotide kinase activity | GO:0005515 ! protein binding | GO:0009152 ! purine ribonucleotide biosynthetic process | GO:0015951 ! purine ribonucleotide interconversion | GO:0016208 ! AMP binding | GO:0015949 ! nucleobase, nucleoside and nucleotide interconversion | Proteins | Location:cytoplasm | Products with structures in PDB

