aidB:Gene Product(s) - EcoliWiki
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aidB:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

Standard name

AidB product

Synonyms

isovaleryl CoA dehydrogenase product[1], B4187 product[2][1], AidB product[2][1]

Product description

EG11811-MONOMER[2][3]

EC number (for enzymes)
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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

QualifierGO IDGO term nameReference(s)Evidence Codewith/fromAspectNotesStatus
GO:0016627

oxidoreductase activity, acting on the CH-CH group of donors

GO_REF:0000002
GO_REF:0000002
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006090
InterPro:IPR009075
InterPro:IPR009100

F

Seeded from EcoCyc 12.5 [4]

complete

GO:0016491

oxidoreductase activity

GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR013764
SP_KW:KW-0560

F

Seeded from EcoCyc 12.5 [4]

complete

GO:0008152

metabolic process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR009100

P

Seeded from EcoCyc 12.5 [4]

complete

GO:0003995

acyl-CoA dehydrogenase activity

GO_REF:0000002
GO_REF:0000002
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006089
InterPro:IPR006091
InterPro:IPR006092

F

Seeded from EcoCyc 12.5 [4]

complete

GO:0003677

DNA binding

PMID:16352838[5]

IPI: Inferred from Physical Interaction

F

Seeded from EcoCyc 12.5 [4]

complete

GO:0006281

DNA repair

PMID:16352838[5]

NR

P

Seeded from EcoCyc 12.5 [4]

complete

GO:0006307

DNA dealkylation

PMID:16352838[5]

NR

P

Seeded from EcoCyc 12.5 [4]

complete

GO:0006950

response to stress

PMID:6330740[6]

IEP: Inferred from Expression Pattern

P

Seeded from EcoCyc 12.5 [4]

complete

GO:0008470

isovaleryl-CoA dehydrogenase activity

PMID:16352838[5]

IDA: Inferred from Direct Assay

F

Seeded from EcoCyc 12.5 [4]

complete

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Interactions

Partner TypePartnerNotesReferences
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Notes

Localization

CompartmentDescriptionEvidenceNotes
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Notes

Structure and Physical Properties

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Physical Properties

Sequence

at EcoCyc

MEGDTVHWQT HTVFNQPIPL NNSNLYLSDG ALCEAVTREG AGWDSDFLAS IGQQLGTAES
LELGRLANVN PPELLRYDAQ GRRLDDVRFH PAWHLLMQAL CTNRVHNLAW EEDARSGAFV
ARAARFMLHA QVEAGSLCPI TMTFAATPLL LQMLPAPFQD WTTPLLSDRY DSHLLPGGQK
RGLLIGMGMT EKQGGSDVMS NTTRAERLED GSYRLVGHKW FFSVPQSDAH LVLAQTAGGL
SCFFVPRFLP DGQRNAIRLE RLKDKLGNRS NASCEVEFQD AIGWLLGLEG EGIRLILKMG
GMTRFDCALG SHAMMRRAFS LAIYHAHQRH VFGNPLIQQP LMRHVLSRMA LQLEGQTALL
FRLARAWDRR ADAKEALWAR LFTPAAKFVI CKRGMPFVAE AMEVLGGIGY CEESELPRLY
REMPVNSIWE GSGNIMCLDV LRVLNKQAGV YDLLSEAFVE VKGQDRYFDR AVRRLQQQLR
KPAEELGREI THQLFLLGCG AQMLKYASPP MAQAWCQVML DTRGGVRLSE QIQNDLLLRA
TGGVCV
Mol. Wt

60.59 kDa (calc) [2]

pI
Extinction coefficient

75400 - 76900 (calc based on 10 Y, 11 W, and 12 C residues)

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Domains/Motifs/Modification Sites

TypeResiduesDescriptionNotes
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Structure

Structures
  • Representative Escherichia coli structure:
    3DJL|A
    1-541 of 546 residues (E-value: 1.1e-296) (Percent Identity: 99.82)
  • Representative homolog:
    2EBA|A (Thermus thermophilus)
    122-373 of 546 residues (E-value: 1.1e-08) (Percent Identity: 27.55)
  • View all other structures.
Models

View models at:

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Notes

Gene Product Resources

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Resource typeSourceNotes/Reference
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Notes

Accessions in Other Databases

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DatabaseAccessionNotes

EcoCyc (EcoliWiki Page)

EcoCyc:EG11811-MONOMER

UniProt (EcoliWiki Page)

UniProt:P33224

PFAM (EcoliWiki Page)

PFAM:PF02771

RefSeq (EcoliWiki Page)

RefSeq:NP_418608

ModBase (EcoliWiki Page)

ModBase:P33224


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Notes

Links

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NameURLComments
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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 4.2 4.3 4.4 4.5 4.6 4.7 4.8 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  5. 5.0 5.1 5.2 5.3 Rohankhedkar MS et al. (2006) The AidB component of the Escherichia coli adaptive response to alkylating agents is a flavin-containing, DNA-binding protein. J Bacteriol 188: 223-30 PubMed EcoliWiki page
  6. Volkert MR & Nguyen DC (1984) Induction of specific Escherichia coli genes by sublethal treatments with alkylating agents. Proc Natl Acad Sci U S A 81: 4110-4 PubMed EcoliWiki page


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