aldA:Gene Product(s) - EcoliWiki
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aldA:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

Standard name

AldA

Synonyms

aldehyde dehydrogenase A, NAD-linked[1], B1415[2][1], Ald[2][1], AldA[2][1]

Product description

AldA[2][3];

Component of ; aldehyde dehydrogenase A, NAD-linked[2][3]

EC number (for enzymes)
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Notes

Function

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Gene Ontology
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QualifierGO IDGO term nameReference(s)Evidence Codewith/fromAspectNotesStatus
GO:0005737

cytoplasm

C

Seeded from Riley et al 2006 [1].

required fields missing

GO:0016052

carbohydrate catabolic process

P

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0009438

methylglyoxal metabolic process

P

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0006113

fermentation

P

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0009441

glycolate metabolic process

P

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0008911

lactaldehyde dehydrogenase activity

PMID:4310089[4]

IDA: Inferred from Direct Assay

F

complete

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Interactions

Partner TypePartnerNotesReferences

Protein

Subunits of aldehyde dehydrogenase A, NAD-linked

could be indirect


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Notes

Localization

CompartmentDescriptionEvidenceNotes
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Notes

Structure and Physical Properties

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Physical Properties

Sequence

at EcoCyc

MSVPVQHPMY IDGQFVTWRG DAWIDVVNPA TEAVISRIPD GQAEDARKAI DAAERAQPEW
EALPAIERAS WLRKISAGIR ERASEISALI VEEGGKIQQL AEVEVAFTAD YIDYMAEWAR
RYEGEIIQSD RPGENILLFK RALGVTTGIL PWNFPFFLIA RKMAPALLTG NTIVIKPSEF
TPNNAIAFAK IVDEIGLPRG VFNLVLGRGE TVGQELAGNP KVAMVSMTGS VSAGEKIMAT
AAKNITKVCL ELGGKAPAIV MDDADLELAV KAIVDSRVIN SGQVCNCAER VYVQKGIYDQ
FVNRLGEAMQ AVQFGNPAER NDIAMGPLIN AAALERVEQK VARAVEEGAR VAFGGKAVEG
KGYYYPPTLL LDVRQEMSIM HEETFGPVLP VVAFDTLEDA ISMANDSDYG LTSSIYTQNL
NVAMKAIKGL KFGETYINRE NFEAMQGFHA GWRKSGIGGA DGKHGLHEYL QTQVVYLQS
Mol. Wt

52.27 kDa (calc) [2]

pI

5.24[2]

Extinction coefficient

59360 - 59735 (calc based on 14 Y, 7 W, and 3 C residues)

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Domains/Motifs/Modification Sites

TypeResiduesDescriptionNotes
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Structure

Structures
  • Representative Escherichia coli structure:
    2HG2|A
    1-479 of 479 residues (E-value: 3.9e-255) (Percent Identity: 100.00)
  • Representative homolog:
    2ESD|A (Streptococcus mutans)
    4-453 of 479 residues (E-value: 1.3e-62) (Percent Identity: 33.48)
  • View all other structures.
Models

View models at:

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Notes

Gene Product Resources

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Resource typeSourceNotes/Reference
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Notes

Accessions in Other Databases

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DatabaseAccessionNotes

EcoCyc (EcoliWiki Page)

EcoCyc:LACTALDDEHYDROG-MONOMER

UniProt (EcoliWiki Page)

UniProt:P25553

PFAM (EcoliWiki Page)

PFAM:PF00171

RefSeq (EcoliWiki Page)

RefSeq:NP_415933

ModBase (EcoliWiki Page)

ModBase:P25553


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Notes

Links

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NameURLComments
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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 3.2 3.3 3.4 3.5 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. Sridhara S & Wu TT (1969) Purification and properties of lactaldehyde dehydrogenase from Escherichia coli. J Biol Chem 244: 5233-8 PubMed EcoliWiki page


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