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alr:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

Standard name

Alr

Synonyms

alanine racemase 1, PLP-binding, biosynthetic[1], B4053[2][1], Alr[2][1]

Product description

Alr[2]; alanine racemase 1, PLP-binding, biosynthetic[3];

Component of ; alanine racemase, minor[2]

EC number (for enzymes)
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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

QualifierGO IDGO term nameReference(s)Evidence Codewith/fromAspectNotesStatus
GO:0009252

peptidoglycan biosynthetic process

GO_REF:0000004
GO_REF:0000020

IEA: Inferred from Electronic Annotation

SP_KW:KW-0573
HAMAP:MF_01201

P

Seeded from EcoCyc 12.5 [4]

complete

GO:0016853

isomerase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0413

F

Seeded from EcoCyc 12.5 [4]

complete

GO:0003824

catalytic activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR009006

F

Seeded from EcoCyc 12.5 [4]

complete

GO:0006522

alanine metabolic process

GO_REF:0000002
GO_REF:0000002
GO_REF:0000020

IEA: Inferred from Electronic Annotation

InterPro:IPR000821
InterPro:IPR011079
HAMAP:MF_01201

P

Seeded from EcoCyc 12.5 [4]

complete

GO:0007047

cell wall organization

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0961

P

Seeded from EcoCyc 12.5 [4]

complete

GO:0008360

regulation of cell shape

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0133

P

Seeded from EcoCyc 12.5 [4]

complete

GO:0008784

alanine racemase activity

GO_REF:0000002
GO_REF:0000002
GO_REF:0000003
GO_REF:0000020

IEA: Inferred from Electronic Annotation

InterPro:IPR000821
InterPro:IPR011079
EC:5.1.1.1
HAMAP:MF_01201

F

Seeded from EcoCyc 12.5 [4]

complete

GO:0030170

pyridoxal phosphate binding

GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_01201

F

Seeded from EcoCyc 12.5 [4]

complete

GO:0005737

cytoplasm

C

Seeded from Riley et al 2006 [1].

required fields missing

GO:0006523

alanine biosynthetic process

P

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0008652

amino acid biosynthetic process

P

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0009063

amino acid catabolic process

P

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0009078

pyruvate family amino acid metabolic process

P

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0006520

amino acid metabolic process

P

Seeded from EcoCyc 11.1[3].

required fields missing

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Interactions

Partner TypePartnerNotesReferences

Protein

Subunits of alanine racemase, minor

could be indirect


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Notes

Localization

CompartmentDescriptionEvidenceNotes
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Notes

Structure and Physical Properties

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Physical Properties

Sequence

at EcoCyc 

MQAATVVINR RALRHNLQRL RELAPASKMV AVVKANAYGH GLLETARTLP DADAFGVARL
EEALRLRAGG ITKPVLLLEG FFDARDLPTI SAQHFHTAVH NEEQLAALEE ASLDEPVTVW
MKLDTGMHRL GVRPEQAEAF YHRLTQCKNV RQPVNIVSHF ARADEPKCGA TEKQLAIFNT
FCEGKPGQRS IAASGGILLW PQSHFDWVRP GIILYGVSPL EDRSTGADFG CQPVMSLTSS
LIAVREHKAG EPVGYGGTWV SERDTRLGVV AMGYGDGYPR AAPSGTPVLV NGREVPIVGR
VAMDMICVDL GPQAQDKAGD PVILWGEGLP VERIAEMTKV SAYELITRLT SRVAMKYVD
Mol. Wt

39.15 kDa (calc) [2]

pI
Extinction coefficient

39420 - 40045 (calc based on 8 Y, 5 W, and 5 C residues)

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Domains/Motifs/Modification Sites

TypeResiduesDescriptionNotes
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Structure

Structures
  • Representative Escherichia coli structure:
    3B8T|A
    21-379 of 359 residues (E-value: 1.1e-191) (Percent Identity: 99.44)
  • Representative homolog:
    2VD9|A (Bacillus anthracis)
    14-376 of 359 residues (E-value: 1.0e-32) (Percent Identity: 31.32)
  • View all other structures.
Models

View models at:

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Notes

Gene Product Resources

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Resource typeSourceNotes/Reference
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Notes

Accessions in Other Databases

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DatabaseAccessionNotes

EcoCyc (EcoliWiki Page)

EcoCyc:ALARACEBIOSYN-MONOMER

UniProt (EcoliWiki Page)

UniProt:P0A6B4

PFAM (EcoliWiki Page)

PFAM:PF01168

RefSeq (EcoliWiki Page)

RefSeq:NP_418477

ModBase (EcoliWiki Page)

ModBase:P0A6B4


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Notes

Links

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NameURLComments
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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 3.2 3.3 3.4 3.5 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 4.2 4.3 4.4 4.5 4.6 4.7 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7


Categories

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