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Quickview

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See Help:Quickview for help with entering information in the Quickview table.

Standard Name

artP

Gene Synonym(s)

ECK0855, b0864, JW0848[1]

Product Desc.

ArtP[2][3];

Component of arginine ABC transporter[2][3]

Arg periplasmic transport system; similarity to transmembrane proteins, BPC ATPases[4]

Product Synonyms(s)

arginine transporter subunit[1], ATP-binding component of ABC superfamily[1], B0864[2][1], ArtP[2][1]

Function from GO
Knock-Out Phenotype
Regulation/Expression

transcription unit(s): artPIQM[2]

Regulation/Activity
Quick Links

DNA display    Protein display    Pubmed(artP)    Textpresso(artP)

See Help:Quickview for help with entering information in the Quickview table.

Notes

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Repressed during biofilm formation.[4]



Gene

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Nomenclature

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See Help:Gene_nomenclature for help with entering information in the Gene Nomenclature table.

Standard name

artP

Mnemonic

Arginine transport

Synonyms

ECK0855, b0864, JW0848[1]

Notes

Location(s) and DNA Sequence

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See Help:Gene_location for help entering information in the Gene Location and DNA sequence table.

StrainMap locationGenome coordinatesGenome browsersSequence links

MG1655

19.45 minutes 

MG1655: 902957..902229
gbrowse_img.php?coord=902229..902957&genome=ecoli&name=MG1655&trackset=0&width=300&.png

REL606

NC_012967: 920441..919713
gbrowse_img.php?coord=919713..920441&genome=REL606&name=NC_012967&trackset=0&width=300&.png

W3110

 

W3110: 904156..903428
gbrowse_img.php?coord=903428..904156&genome=ecoli_W3110&name=W3110&trackset=0&width=300&.png

DH10B

DH10B: 956885..956157
gbrowse_img.php?coord=956157..956885&genome=ecoli_DH10B&name=DH10B&trackset=0&width=300&.png

BW2952

NC_012759: 805197..805925
gbrowse_img.php?coord=805197..805925&genome=BW2952&name=NC_012759&trackset=0&width=300&.png

Notes

Sequence Features

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See Help:Gene_sequence_features for help in entering sequence features in EcoliWiki.

Feature typeLocationDescription

Notes

Alleles and Phenotypes

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See Help:Gene_alleles for how to enter or edit alleles and phenotypes in EcoliWiki.

AlleleNt change(s)AA change(s)Phenotype: TypePhenotype: DescriptionReferenceAvailabilityComments

ΔartP (Keio:JW0848)

deletion

deletion

PMID:16738554

Shigen
CGSC8884[5]

ΔartP765::kan

PMID:16738554

CGSC:100094


Notes

Genetic Resources

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See Help:Gene_resources for help entering information into the Genetic Resources table.

ResourceResource TypeSourceNotes/Reference

JW0848

Plasmid clone

Shigen

PMID:16769691

Status:Clone OK

Primer 1:GCCAGTATTCAATTAAACGGCAT

Primer 2:CCGTGAGAGAGATAGTTTTTAAA

zbh-29::Tn10

Linked marker

CAG18493 = CGSC7353[5]

est. P1 cotransduction: % [6]
Synonyms:zbi-29::Tn10

zca-1230::Tn10

Linked marker

CAG18478 = CGSC7356[5]

est. P1 cotransduction: 14% [6]
Synonyms:zbj-1230::Tn10

Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

DatabaseAccessionNotes

EcoCyc (EcoliWiki Page)

EcoCyc:EG11624

EchoBASE (EcoliWiki Page)

EchoBASE:EB1581

EcoliGenExpDB (EcoliWiki Page)

EcoliGenExpDB:b0864

ECOL199310CYC (EcoliWiki Page)

ECOL199310CYC:C0997

EcoGene (EcoliWiki Page)

EcoGene:EG11624

ECOO157CYC (EcoliWiki Page)

ECOO157CYC:ARTP

CGSC (EcoliWiki Page)

CGSC:31677

ASAP (EcoliWikiPage)

ASAP:ABE-0002939


Notes

Links

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Product(s)

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Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

ArtP

Synonyms

arginine transporter subunit[1], ATP-binding component of ABC superfamily[1], B0864[2][1], ArtP[2][1]

Product description

ArtP[2][3];

Component of arginine ABC transporter[2][3]

Arg periplasmic transport system; similarity to transmembrane proteins, BPC ATPases[4]

EC number (for enzymes)


Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

QualifierGO IDGO term nameReference(s)Evidence Codewith/fromAspectNotesStatus

GO:0016887

ATPase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003439

F

Seeded from EcoCyc 12.5 [7]

complete

GO:0017111

nucleoside-triphosphatase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003593

F

Seeded from EcoCyc [8]

complete

GO:0016020

membrane

GO_REF:0000004
GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0397
SP_KW:KW-0472

C

Seeded from EcoCyc 12.5 [7]

complete

GO:0006810

transport

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0813

P

Seeded from EcoCyc [8]

complete

GO:0006865

amino acid transport

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0029

P

Seeded from EcoCyc [8]

complete

GO:0005524

ATP binding

GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR003439
SP_KW:KW-0067

F

Seeded from EcoCyc 12.5 [7]

complete

GO:0000166

nucleotide binding

GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR003593
SP_KW:KW-0547

F

Seeded from EcoCyc [8]

complete

GO:0006526

arginine biosynthetic process

P

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0005886

plasma membrane

GO_REF:0000004
GO_REF:0000004
GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_KW:KW-0997
SP_KW:KW-1003
SP_SL:SL-0037

C

Seeded from EcoCyc [8]

complete

GO:0005737

cytoplasm

C

Seeded from EcoCyc 11.1[3].

required fields missing

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner TypePartnerNotesReferencesEvidence

Protein

Subunits of arginine ABC transporter

could be indirect

Protein

ppk

PMID:15690043

Experiment(s):EBI-892681

Protein

topA

PMID:15690043

Experiment(s):EBI-892681

Protein

yccA

PMID:15690043

Experiment(s):EBI-892681

Protein

nadE

PMID:16606699

Experiment(s):EBI-1138211

Protein

ygfH

PMID:16606699

Experiment(s):EBI-1138211

Protein

groL

PMID:16606699

Experiment(s):EBI-1138211

Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

CompartmentDescriptionEvidenceSourceNotes

cytoplasm

From EcoCyc[3]

Cytoplasm

PMID:8801422, PMID:15758229

EchoLocation:artP


Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Sequence

at EcoCyc

MSIQLNGINC FYGAHQALFD ITLDCPQGET LVLLGPSGAG KSSLLRVLNL LEMPRSGTLN
IAGNHFDFTK TPSDKAIRDL RRNVGMVFQQ YNLWPHLTVQ QNLIEAPCRV LGLSKDQALA
RAEKLLERLR LKPYSDRYPL HLSGGQQQRV AIARALMMEP QVLLFDEPTA ALDPEITAQI
VSIIRELAET NITQVIVTHE VEVARKTASR VVYMENGHIV EQGDASCFTE PQTEAFKNYL SH
Length

242

Mol. Wt

27.022 kDa

pI

6.6 (calculated)

Extinction coefficient

14,440 - 14,940 (calc based on 6 Y, 1 W, and 4 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

TypeResiduesDescriptionNotesReferences


Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures
Models

View models at:

Structure figures

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource typeSourceNotes/Reference

Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

DatabaseAccessionNotes

EcoCyc (EcoliWiki Page)

EcoCyc:ARTP-MONOMER

SwissModel (EcoliWiki Page)

SwissModel:P0AAF6

UniProt (EcoliWiki Page)

UniProt:P0AAF6

PFAM (EcoliWiki Page)

PFAM:PF00005

RefSeq (EcoliWiki Page)

RefSeq:NP_415385


Notes

Links

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Expression

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Overview

This is a placeholder for a summary statement on how expression of this gene product is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.


Cellular Levels

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See Help:Cellular levels

MoleculeOrganism or StrainCellular levelUnitsMediumTemperature °COther (e.g. anaerobic)Growth rateAssay usedNotesReference(s)

Notes

Transcription and Transcriptional Regulation

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See Help:Expression_transcription for help entering or editing information in this section of EcoliWiki.

Transcription unit(s)

artPIQM

Figure courtesy of RegulonDB

Notes

This is a placeholder for a summary statement about how transcription of this gene is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.

Translation and Regulation of Translation

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gbrowse_img.php?coord=902937..902977&genome=ecoli&name=MG1655&trackset=Gene+DNA_+Protein+flip&width=400&figure=Nterm&.png
This picture shows the sequence around the N-terminus.

Notes

This is a placeholder for a summary statement about how translation of this gene product is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.

Turnover and Regulation of Turnover

Notes

This is a placeholder for a summary statement about turnover of this gene product. You can help EcoliWiki by becoming a user and writing/editing this statement.

Experimental

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Mutations Affecting Expression See Help:Expression_mutations for help entering or editing information in this section of EcoliWiki.

Allele NameMutationPhenotypeReference


Expression Studies See Help:Expression_studies for help entering or editing information in this section of EcoliWiki.

TypeReferenceNotes

microarray

GEO Profiles:b0864 (EcoliWiki Page)

NCBI GEO profiles for artP

microarray

GenExpDB:b0864 (EcoliWiki Page)

Summary of data for artP from multiple microarray studies


Expression Resources See Help:Expression_resources for help entering or editing information in this section of EcoliWiki.

Resource NameResource TypeDescriptionSourceNotes

GFP Fusion

Intergenic region (902881..903252) fused to gfpmut2.

OpenBioSystems

GFP fusion described in Zaslaver, et al.
Plate:109-AZ14; Well:C7[9]

Notes

Accessions Related to artP Expression

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

DatabaseAccessionNotes

EcoCyc (EcoliWiki Page)

EcoCyc:EG11624

EchoBASE (EcoliWiki Page)

EchoBASE:EB1581

EcoliGenExpDB (EcoliWiki Page)

EcoliGenExpDB:b0864

EcoGene (EcoliWiki Page)

EcoGene:EG11624


Notes

Links

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Evolution

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Homologs in Other Organisms

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See Help:Evolution_homologs for help entering or editing information in this section of EcoliWiki.

OrganismHomologs (Statistics)Comments

Takifugu rubripes

  • NEWSINFRUP00000130824 (score: 1.000; bootstrap: 57%)
  • NEWSINFRUP00000130826 (score: 0.180)
  • NEWSINFRUP00000167567 (score: 0.137)
  • NEWSINFRUP00000182359 (score: 0.125)
  • NEWSINFRUP00000177047 (score: 0.125)
  • NEWSINFRUP00000168237 (score: 0.097)
  • NEWSINFRUP00000171182 (score: 0.092)

From Inparanoid:20070104

Tetraodon nigroviridis

  • GSTENP00014344001 (score: 1.000; bootstrap: 57%)
  • GSTENP00014343001 (score: 0.105)
  • GSTENP00020877001 (score: 0.101)
  • GSTENP00038511001 (score: 0.091)
  • GSTENP00014937001 (score: 0.051)

From Inparanoid:20070104

Shigella flexneri

ARTP

From SHIGELLACYC

E. coli O157

ARTP

From ECOO157CYC


Do-It-Yourself Web Tools

Notes

Families

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

DatabaseAccessionNotes

PFAM (EcoliWiki Page)

PFAM:PF00005


Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 1.9 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 2.8 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 3.2 3.3 3.4 3.5 3.6 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 4.2 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. 5.0 5.1 5.2 CGSC: The Coli Genetics Stock Center
  6. 6.0 6.1 The Tn10 insertion sites determined by Nichols et al. 1998 (PMID:9829956) were reannotated by alignment with E. coli K-12 genome sequence (GenBank accession NC_000913). P1 contransduction frequencies were calculated using the formula of Wu (PMID:5338813).
  7. 7.0 7.1 7.2 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  8. 8.0 8.1 8.2 8.3 8.4 EcoCyc (release 13.0; 2009) Keseler, IM et al. (2009) Nucleic Acids Res. 37(Database issue):D464-70
  9. Zaslaver A et al. (2006) A comprehensive library of fluorescent transcriptional reporters for Escherichia coli. Nat Methods 3: 623-8 PubMed EcoliWiki page

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