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barA:Quickview

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Standard Name

barA

Gene Synonym(s)

ECK2780, b2786, JW2757, airS(S.t.)[1][2], airS, gacC

Product Desc.

hybrid sensory histidine kinase, in two-component regulatory system with UvrY[1] Sensor histidine protein kinase, pleiotropic; controls the expresion of csrB/C sRNAs; works in concert with UvrY response regulator[3]

Product Synonyms(s)

B2786[2][1], AirS[4], airS, ECK2780, gacC, JW2757, b2786

Function from GO
Knock-Out Phenotype
Regulation/Expression

transcription unit(s): barA[2]

Regulation/Activity
Quick Links

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Notes

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BarA has both sensory kinase and response regulator domains. BarA is required for catalase (KatE) expression and resistance to hydrogen peroxide, through rpoS regulation.[3]. BarA is activated by short chain carbxylates.



References

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  1. 1.0 1.1 1.2 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  4. Pernestig, AK et al. (2001) Identification of UvrY as the cognate response regulator for the BarA sensor kinase in Escherichia coli. J. Biol. Chem. 276 225-31 PubMed EcoliWiki page