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References Suggestions

Standard Name


Gene Synonym(s)

ECK4105, b4112, JW4073, pmrB[1], pmrB

Product Desc.

sensory histidine kinase in two-component regulatory system with BasR[1]

Histidine protein kinase sensor Lipid A modification genes; two-component system involved in polymyxin resistance that senses high extracellular Fe(2+)[2]

Product Synonyms(s)

B4112[3][1], PmrB[3][1], ECK4105, JW4073, pmrB, b4112

Function from GO
Knock-Out Phenotype

transcription unit(s): basRS[3]

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BasR is the cognate response regulator of the BasSR two-component system. The BasSR regulon has been primarily characterized in Salmonella; unlike E. coli, Salmonella also activates PmrAB(BasSR) in low Mg(2+), mediated by PhoPQ and the PmrD protein.[2]


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  1. 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  3. 3.0 3.1 3.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7