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caiF:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

CaiF

Synonyms

DNA-binding transcriptional activator[1], B0034[2][1], CaiF[2][1]

Product description

CaiF transcriptional activator[2][3]

Transcriptional activator of cai operon[4]

EC number (for enzymes)


Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

QualifierGO IDGO term nameReference(s)Evidence Codewith/fromAspectNotesStatus
GO:0006350

transcription

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0804

P

Seeded from EcoCyc 12.5 [5]

complete

GO:0006355

regulation of transcription, DNA-dependent

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0805

P

Seeded from EcoCyc [6]

complete

GO:0006350

transcription

PMID:10564497[7]

IDA: Inferred from Direct Assay

P

Seeded from EcoCyc 12.5 [5]

complete

GO:0006350

transcription

PMID:8631699[8]

IEP: Inferred from Expression Pattern

P

Seeded from EcoCyc 12.5 [5]

complete

GO:0006350

transcription

PMID:9573142[9]

IEP: Inferred from Expression Pattern

P

Seeded from EcoCyc 12.5 [5]

complete

GO:0005737

cytoplasm

C

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0016563

transcription activator activity

F

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0009310

amine catabolic process

P

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0016563

transcription activator activity

PMID:8631699[8]

EXP: Inferred from Experiment

F

Seeded from EcoCyc 11.1[3].

complete

GO:0009437

carnitine metabolic process

PMID:8631699[8]

EXP: Inferred from Experiment

P

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner TypePartnerNotesReferencesEvidence

Protein

sdhA

PMID:16606699[10]

Experiment(s):EBI-1135382

Protein

tatE

PMID:16606699[10]

Experiment(s):EBI-1135382

Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

CompartmentDescriptionEvidenceSourceNotes

Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Sequence

at EcoCyc

MKLHTIDIST ILIWPCLIAS KRVIARLLIC ETGVRMCEGY VEKPLYLLIA EWMMAENRWV
IAREISIHFD IEHSKAVNTL TYILSEVTEI SCEVKMIPNK LEGRGCQCQR LVKVVDIDEQ
IYARLRNNSR EKLVGVRKTP RIPAVPLTEL NREQKWQMML SKSMRR
Length

166

Mol. Wt

19.396 kDa

pI

9.2 (calculated)

Extinction coefficient

27,960 - 28,710 (calc based on 4 Y, 4 W, and 6 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

TypeResiduesDescriptionNotesReferences


Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures
Models

View models at:

Structure figures

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource typeSourceNotes/Reference

Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

DatabaseAccessionNotes

EcoCyc (EcoliWiki Page)

EcoCyc:G6088-MONOMER

UniProt (EcoliWiki Page)

UniProt:P0AE58

RefSeq (EcoliWiki Page)

RefSeq:NP_414576


Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 3.2 3.3 3.4 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. 5.0 5.1 5.2 5.3 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  6. EcoCyc (release 13.0; 2009) Keseler, IM et al. (2009) Nucleic Acids Res. 37(Database issue):D464-70
  7. Buchet A et al. (1999) Positive co-regulation of the Escherichia coli carnitine pathway cai and fix operons by CRP and the CaiF activator. Mol Microbiol 34: 562-75 PubMed EcoliWiki page
  8. 8.0 8.1 8.2 Eichler K et al. (1996) Identification and characterization of the caiF gene encoding a potential transcriptional activator of carnitine metabolism in Escherichia coli. J Bacteriol 178: 1248-57 PubMed EcoliWiki page
  9. Buchet A et al. (1998) Regulation of the carnitine pathway in Escherichia coli: investigation of the cai-fix divergent promoter region. J Bacteriol 180: 2599-608 PubMed EcoliWiki page
  10. 10.0 10.1 Arifuzzaman M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res 16: 686-91 PubMed EcoliWiki page

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