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ccmB:Gene Product(s)
From EcoliWiki
| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| Nomenclature | Function | Interactions | Localization | Sequence | Domains | Structure | Resources | Accessions | Links | References | Suggestions |
Nomenclature
See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.
| Standard name |
CcmB |
|---|---|
| Synonyms |
heme exporter subunit[1], membrane component of ABC superfamily[1], B2200[2][1], YejV[2][1], CcmB[2][1] |
| Product description |
Component of CcmABC ABC transporter[2][3]; [[:Category:Complex:CcmABCDEFGH cytochrome c biogenesis system|CcmABCDEFGH cytochrome c biogenesis system]][3] ABC transporter, ATPase subunit; CcmABCD transporter complex; probably not heme exporter[4] |
| EC number (for enzymes) |
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| edit table |
Notes
Function
Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.
| Qualifier | GO ID | GO term name | Reference(s) | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0016021 |
integral to membrane |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc [5] |
complete | |||
| GO:0005515 |
protein binding |
IPI: Inferred from Physical Interaction |
F |
Seeded from EcoCyc [5] |
complete | |||
| GO:0015439 |
heme-transporting ATPase activity |
IMP: Inferred from Mutant Phenotype |
F |
Seeded from EcoCyc [5] |
complete | |||
| GO:0015886 |
heme transport |
IGI: Inferred from Genetic Interaction |
P |
Seeded from EcoCyc 12.5 [8] |
complete | |||
| GO:0017004 |
cytochrome complex assembly |
IMP: Inferred from Mutant Phenotype |
P |
Seeded from EcoCyc 12.5 [8] |
complete | |||
| GO:0043190 |
ATP-binding cassette (ABC) transporter complex |
IMP: Inferred from Mutant Phenotype |
C |
Seeded from EcoCyc [5] |
complete | |||
| GO:0006457 |
protein folding |
P |
Seeded from EcoCyc 11.1[3]. |
required fields missing | ||||
| GO:0005886 |
plasma membrane |
IEA: Inferred from Electronic Annotation |
SP_KW:KW-0997 |
C |
Seeded from EcoCyc [5] |
complete | ||
| GO:0006810 |
transport |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc [5] |
complete | |||
| GO:0015232 |
heme transporter activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc [5] |
complete | |||
| GO:0016020 |
membrane |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc [5] |
complete | |||
| edit table |
Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.
| Partner Type | Partner | Notes | References | Evidence |
|---|---|---|---|---|
|
Protein |
Subunits of CcmABC ABC transporter |
could be indirect | ||
|
Protein |
Subunits of [[:Category:Complex:CcmABCDEFGH cytochrome c biogenesis system|CcmABCDEFGH cytochrome c biogenesis system]] |
could be indirect |
| |
| edit table |
Notes
Localization
See Help:Product_localization for how to add or edit information in this section of EcoliWiki.
| Compartment | Description | Evidence | Source | Notes |
|---|---|---|---|---|
|
plasma membrane |
C-terminus localized in the cytoplasm with 6 predicted transmembrane domains |
Daley et al. (2005) [10] | ||
|
plasma membrane |
From EcoCyc[3] |
| ||
| edit table |
Notes
Structure and Physical Properties
Physical Properties
See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.
| Sequence |
MMFWRIFRLE LRVAFRHSAE IANPLWFFLI VITLFPLSIG PEPQLLARIA PGIIWVAALL SSLLALERLF RDDLQDGSLE QLMLLPLPLP AVVLAKVMAH WMVTGLPLLI LSPLVAMLLG MDVYGWQVMA LTLLLGTPTL GFLGAPGVAL TVGLKRGGVL LSILVLPLTI PLLIFATAAM DAASMHLPVD GYLAILGALL AGTATLSPFA TAAALRISIQ |
|---|---|
| Length |
220 |
| Mol. Wt |
23.62 kDa |
| pI |
7.5 (calculated) |
| Extinction coefficient |
30,480 (calc based on 2 Y, 5 W, and C residues) |
| edit table |
Domains/Motifs/Modification Sites
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See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.
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Structure
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Structure figures
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| Resource type | Source | Notes/Reference |
|---|---|---|
| edit table |
Notes
Accessions in Other Databases
See Help:Gene_accessions for help with entering information into the Gene Accessions table.
| Database | Accession | Notes |
|---|---|---|
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| ||
| edit table |
Notes
Links
| Name | URL | Comments |
|---|---|---|
| edit table |
References
See Help:References for how to manage references in EcoliWiki.
- ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 3.2 3.3 3.4 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
- ↑ 5.0 5.1 5.2 5.3 5.4 5.5 5.6 5.7 EcoCyc (release 13.0; 2009) Keseler, IM et al. (2009) Nucleic Acids Res. 37(Database issue):D464-70
- ↑ 6.0 6.1 6.2 Feissner RE et al. (2006) ABC transporter-mediated release of a haem chaperone allows cytochrome c biogenesis. Mol Microbiol 61: 219-31 PubMed EcoliWiki page
- ↑ Christensen O et al. (2007) Loss of ATP hydrolysis activity by CcmAB results in loss of c-type cytochrome synthesis and incomplete processing of CcmE. FEBS J 274: 2322-32 PubMed EcoliWiki page
- ↑ 8.0 8.1 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ Thony-Meyer L et al. (1995) Escherichia coli genes required for cytochrome c maturation. J Bacteriol 177: 4321-6 PubMed EcoliWiki page
- ↑ Daley DO et al. (2005) Global topology analysis of the Escherichia coli inner membrane proteome. Science 308: 1321-3 PubMed EcoliWiki page
Categories
[[Category:Complex:CcmABCDEFGH cytochrome c biogenesis system]]
