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chbR:Quickview
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| Standard Name |
chbR |
|---|---|
| Gene Synonym(s) |
ECK1733, b1735, JW1724, celD[1] |
| Product Desc. |
ChbR transcriptional regulator[2]; ChbR transcriptional dual regulator[3] Repressor, chb operon for N,N'-diacetylchitobiose utilization; AraC family [4] |
| Product Synonyms(s) |
DNA-binding transcriptional dual regulator[1], B1735[2][1], ChbR[2][1], CelD[2][1] |
| Function from GO |
Molecular Function |
| Knock-Out Phenotype |
Chitobiose negative and Cellobiose negative |
| Regulation/Expression | |
| Regulation/Activity |
Repressor in the absence of inducer and activator in the presence of inducer. |
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Notes
ChbR was initially reported as a repressor of the chb operon. However later work showed that this protein is an activator as well as the repressor of the chb operon. The mutations in the chbR have also been reported to confer Cel+ phenotype to E. coli.
References
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- ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
- ↑ Kachroo AH et al. (2007) Mutations that alter the regulation of the chb operon of Escherichia coli allow utilization of cellobiose. Mol Microbiol 66: 1382-95 PubMed EcoliWiki page
- ↑ Plumbridge J & Pellegrini O (2004) Expression of the chitobiose operon of Escherichia coli is regulated by three transcription factors: NagC, ChbR and CAP. Mol Microbiol 52: 437-49 PubMed EcoliWiki page
- ↑ Keyhani NO & Roseman S (1997) Wild-type Escherichia coli grows on the chitin disaccharide, N,N'-diacetylchitobiose, by expressing the cel operon. Proc Natl Acad Sci U S A 94: 14367-71 PubMed EcoliWiki page
