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clpB:Gene Product(s)
From EcoliWiki
| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| Nomenclature | Function | Interactions | Localization | Sequence | Domains | Structure | Resources | Accessions | Links | References | Suggestions |
Nomenclature
See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.
| Standard name |
ClpB |
|---|---|
| Synonyms |
protein disaggregation chaperone[1], B2592[2][1], HtpM[2][1], ClpB[2][1], F84.1[2][1], F68.5[2][1], E89[2][1] |
| Product description |
ATP-dependent protease and chaperone; protein disaggregation chaperone; role in de novo protein folding under mild stress conditions[4] |
| EC number (for enzymes) |
|
| edit table |
Notes
Function
Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.
| Qualifier | GO ID | GO term name | Reference(s) | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005524 |
ATP binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc 12.5 [5] |
complete | |||
| GO:0005515 |
protein binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc [6] |
complete | |||
| GO:0000166 |
nucleotide binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc [6] |
complete | |||
| GO:0005737 |
cytoplasm |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc 12.5 [5] |
complete | |||
| GO:0006950 |
response to stress |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc [6] |
complete | |||
| GO:0017111 |
nucleoside-triphosphatase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc [6] |
complete | |||
| GO:0019538 |
protein metabolic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc [6] |
complete | |||
| GO:0005624 |
membrane fraction |
IDA: Inferred from Direct Assay |
C |
Seeded from EcoCyc [6] |
complete | |||
| GO:0006457 |
protein folding |
P |
Seeded from EcoCyc 11.1[3]. |
required fields missing | ||||
| GO:0005739 |
mitochondrion |
IDA: Inferred from Direct Assay |
C |
Seeded from EcoCyc [6] |
complete | |||
| GO:0005829 |
cytosol |
IDA: Inferred from Direct Assay |
C |
Seeded from EcoCyc [6] |
complete | |||
| GO:0009050 |
glycopeptide catabolic process |
P |
Seeded from EcoCyc 11.1[3]. |
required fields missing | ||||
| edit table |
Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.
| Partner Type | Partner | Notes | References | Evidence |
|---|---|---|---|---|
|
Protein |
Experiment(s):EBI-884811 | |||
|
Protein |
Experiment(s):EBI-884811 | |||
|
Protein |
Experiment(s):EBI-891673 | |||
|
Protein |
Experiment(s):EBI-891673 | |||
|
Protein |
Experiment(s):EBI-891673 | |||
|
Protein |
Experiment(s):EBI-891673 | |||
|
Protein |
Experiment(s):EBI-891673 | |||
|
Protein |
Experiment(s):EBI-891673 | |||
|
Protein |
Experiment(s):EBI-891673 | |||
|
Protein |
Experiment(s):EBI-891673 | |||
|
Protein |
Experiment(s):EBI-891673 | |||
|
Protein |
Experiment(s):EBI-891673 | |||
|
Protein |
Experiment(s):EBI-891673 | |||
|
Protein |
Experiment(s):EBI-891673 | |||
|
Protein |
Experiment(s):EBI-891673 | |||
|
Protein |
Experiment(s):EBI-891673 | |||
|
Protein |
Experiment(s):EBI-891673 | |||
|
Protein |
Experiment(s):EBI-891673 | |||
|
Protein |
Experiment(s):EBI-891673 | |||
|
Protein |
Experiment(s):EBI-891673 | |||
|
Protein |
Experiment(s):EBI-891673 | |||
|
Protein |
Experiment(s):EBI-891673 | |||
|
Protein |
Experiment(s):EBI-891673 | |||
|
Protein |
Experiment(s):EBI-891673 | |||
|
Protein |
Experiment(s):EBI-1143404 | |||
|
Protein |
Experiment(s):EBI-1143404 | |||
|
Protein |
Experiment(s):EBI-1143404 | |||
|
Protein |
Experiment(s):EBI-1143404 | |||
|
Protein |
Experiment(s):EBI-1143404 | |||
|
Protein |
Experiment(s):EBI-1143404 | |||
|
Protein |
Experiment(s):EBI-1143404 | |||
|
Protein |
Experiment(s):EBI-1143404 | |||
|
Protein |
Experiment(s):EBI-1143404 | |||
|
Protein |
Experiment(s):EBI-1143404 | |||
|
Protein |
Experiment(s):EBI-1143404 | |||
| edit table |
Notes
Localization
See Help:Product_localization for how to add or edit information in this section of EcoliWiki.
| Compartment | Description | Evidence | Source | Notes |
|---|---|---|---|---|
|
cytoplasm |
| |||
| edit table |
Notes
Structure and Physical Properties
Physical Properties
See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.
| Sequence |
MRLDRLTNKF QLALADAQSL ALGHDNQFIE PLHLMSALLN QEGGSVSPLL TSAGINAGQL RTDINQALNR LPQVEGTGGD VQPSQDLVRV LNLCDKLAQK RGDNFISSEL FVLAALESRG TLADILKAAG ATTANITQAI EQMRGGESVN DQGAEDQRQA LKKYTIDLTE RAEQGKLDPV IGRDEEIRRT IQVLQRRTKN NPVLIGEPGV GKTAIVEGLA QRIINGEVPE GLKGRRVLAL DMGALVAGAK YRGEFEERLK GVLNDLAKQE GNVILFIDEL HTMVGAGKAD GAMDAGNMLK PALARGELHC VGATTLDEYR QYIEKDAALE RRFQKVFVAE PSVEDTIAIL RGLKERYELH HHVQITDPAI VAAATLSHRY IADRQLPDKA IDLIDEAASS IRMQIDSKPE ELDRLDRRII QLKLEQQALM KESDEASKKR LDMLNEELSD KERQYSELEE EWKAEKASLS GTQTIKAELE QAKIAIEQAR RVGDLARMSE LQYGKIPELE KQLEAATQLE GKTMRLLRNK VTDAEIAEVL ARWTGIPVSR MMESEREKLL RMEQELHHRV IGQNEAVDAV SNAIRRSRAG LADPNRPIGS FLFLGPTGVG KTELCKALAN FMFDSDEAMV RIDMSEFMEK HSVSRLVGAP PGYVGYEEGG YLTEAVRRRP YSVILLDEVE KAHPDVFNIL LQVLDDGRLT DGQGRTVDFR NTVVIMTSNL GSDLIQERFG ELDYAHMKEL VLGVVSHNFR PEFINRIDEV VVFHPLGEQH IASIAQIQLK RLYKRLEERG YEIHISDEAL KLLSENGYDP VYGARPLKRA IQQQIENPLA QQILSGELVP GKVIRLEVNE DRIVAVQ |
|---|---|
| Length |
857 |
| Mol. Wt |
95.587 kDa |
| pI |
5.3 (calculated) |
| Extinction coefficient |
36,330 - 36,705 (calc based on 17 Y, 2 W, and 3 C residues) |
| edit table |
|
See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.
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Structure
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Structure figures
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| Resource type | Source | Notes/Reference |
|---|---|---|
| edit table |
Notes
Accessions in Other Databases
See Help:Gene_accessions for help with entering information into the Gene Accessions table.
| Database | Accession | Notes |
|---|---|---|
|
| ||
| edit table |
Notes
Links
| Name | URL | Comments |
|---|---|---|
| edit table |
References
See Help:References for how to manage references in EcoliWiki.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 3.2 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
- ↑ 5.0 5.1 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 6.0 6.1 6.2 6.3 6.4 6.5 6.6 6.7 EcoCyc (release 13.0; 2009) Keseler, IM et al. (2009) Nucleic Acids Res. 37(Database issue):D464-70
- ↑ 7.0 7.1 7.2 Lasserre JP et al. (2006) A complexomic study of Escherichia coli using two-dimensional blue native/SDS polyacrylamide gel electrophoresis. Electrophoresis 27: 3306-21 PubMed EcoliWiki page
- ↑ 8.00 8.01 8.02 8.03 8.04 8.05 8.06 8.07 8.08 8.09 8.10 8.11 8.12 8.13 8.14 8.15 8.16 8.17 8.18 8.19 8.20 8.21 8.22 8.23 Butland G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433: 531-7 PubMed EcoliWiki page
- ↑ 9.00 9.01 9.02 9.03 9.04 9.05 9.06 9.07 9.08 9.09 9.10 Arifuzzaman M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res 16: 686-91 PubMed EcoliWiki page
