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crl:Quickview
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| Standard Name |
crl |
|---|---|
| Gene Synonym(s) |
ECK0241, b0240, JW0230[1] |
| Product Desc. |
Crl transcriptional regulator[2][3] Stimulates RNA polymerase holoenzyme formation; stimulates RpoS activity during stationary phase; mutants display rpoS mutant phenocopy; does not reduce amount of RpoS protein[4] |
| Product Synonyms(s) |
DNA-binding transcriptional regulator[1], B0240[2][1], Crl[2][1] |
| Function from GO |
Molecular Function |
| Knock-Out Phenotype | |
| Regulation/Expression | |
| Regulation/Activity | |
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Notes
RpoD, RpoS and RpoH sigma factor-containing holoenzyme assembly is stimulated by Crl (Gaal, 2006). Accumulation of Crl during stationary phase at 30C, but not 37C, suggests it is a thermosensor controlling sigma(S) activity. Initially identified due to reduction of RpoS-dependent curlin (csgAB) expression.[4]
References
- ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
