PortEco logo


From EcoliWiki
(Redirected from cspA)
Jump to: navigation, search

Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

Standard Name


Gene Synonym(s)

ECK3543, b3556, JW3525[1], JW3525

Product Desc.

CspA transcriptional activator[2][3]

Cold-inducible RNA chaperone and anti-terminator; aids gene expression at low temperature; cold shock protein CS7.4; binds ssRNA and ssDNA[4]

Product Synonyms(s)

major cold shock protein[1], B3556[2][1], CspA[2][1], major cold shock protein 7.4[2][1], CS7.4[2][1], F10.6[2][1], cold shock protein CspA[2][1] , ECK3543, JW3525, b3556

Function from GO

Biological Process

Molecular Function

Knock-Out Phenotype

transcription unit(s): cspA[2]

Quick Links

porteco.png EcoCyc.gif regulondb.jpg

dnadisplay.png proteindisplay.png   pubmed.jpg   textpresso.jpg  

See Help:Quickview for help with entering information in the Quickview table.


[back to top]

The cspABEG deletion BX04 is cold-sensitive and forms filaments at 15C (Xia, 2001). A cspA deletion grows slow below 8C (as enabled by transgenic Oleispira antarctica Cpn10/60). CspA is similar to Y-box DNA binding proteins of eukaryotes. Mutant has increased aggregation. Binds TrxA (Kumar, 2004).[4]


[back to top]

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.