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Standard Name


Gene Synonym(s)

yhdA, ECK3240, b3252, JW3221[1][2], JW3221

Product Desc.

regulator of CsrB and CsrC decay[2][3]

Targets csrB/C sRNAs for degradation by RNase E; carbon flux regulator; mechanism unknown; indirectly affects CsrA function[4]

Product Synonyms(s)

conserved inner membrane protein[1], B3252[2][1], YhdA[2][1], CsrD[2][1] , ECK3240, JW3221, yhdA, b3252

Function from GO
Knock-Out Phenotype

transcription unit(s): yhdA[2]

Quick Links

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CsrD has a central GGDEF putative diguanylate cyclase, then a C-terminal putative cyclic-di-GMP phosphodiesterase EAL domain. CsrD's role in csrB/C destabilization does not involve cyclic-di-GMP metabolism; very low level of CsrD expression; CsrD may work at substoichiometric concentrations (Suzuki, 2006). False positive lipoprotein prediction, Cys not conserved.[4]


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  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.