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dcm:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

Dcm

Synonyms

DNA cytosine methylase[1], B1961[2][1], Mec[2][1], Dcm[2][1]

Product description

DNA cytosine methylase[2][3]

DNA cytosine methyltransferase; internal cytosine methylated[4]

EC number (for enzymes)

Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

QualifierGO IDGO term nameReference(s)Evidence Codewith/fromAspectNotesStatus
GO:0003677

DNA binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001525

F

Seeded from EcoCyc 12.5 [5]

complete

GO:0003886

DNA (cytosine-5-)-methyltransferase activity

GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:2.1.1.37

F

Seeded from EcoCyc [6]

complete

GO:0006306

DNA methylation

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001525

P

Seeded from EcoCyc 12.5 [5]

complete

GO:0008168

methyltransferase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0489

F

Seeded from EcoCyc [6]

complete

GO:0009307

DNA restriction-modification system

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0680

P

Seeded from EcoCyc [6]

complete

GO:0016740

transferase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0808

F

Seeded from EcoCyc [6]

complete

GO:0005515

protein binding

PMID:15690043[7]

IPI: Inferred from Physical Interaction

UniProtKB:P06959

F

Seeded from EcoCyc [6]

complete

GO:0005737

cytoplasm

C

Seeded from EcoCyc 11.1[3].

required fields missing

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner TypePartnerNotesReferencesEvidence

Protein

amn

PMID:16606699[8]

Experiment(s):EBI-1141506

Protein

rplB

PMID:16606699[8]

Experiment(s):EBI-1141506

Protein

rimK

PMID:16606699[8]

Experiment(s):EBI-1141506

Protein

mukB

PMID:16606699[8]

Experiment(s):EBI-1141506

Protein

yedV

PMID:16606699[8]

Experiment(s):EBI-1141506

Protein

groL

PMID:16606699[8]

Experiment(s):EBI-1141506

Protein

purR

PMID:16606699[8]

Experiment(s):EBI-1141506

Protein

rplA

PMID:15690043[7]

Experiment(s):EBI-894157

Protein

rplC

PMID:15690043[7]

Experiment(s):EBI-894157

Protein

rplM

PMID:15690043[7]

Experiment(s):EBI-894157

Protein

rplU

PMID:15690043[7]

Experiment(s):EBI-894157

Protein

rplV

PMID:15690043[7]

Experiment(s):EBI-894157

Protein

rpsC

PMID:15690043[7]

Experiment(s):EBI-894157

Protein

rpsE

PMID:15690043[7]

Experiment(s):EBI-894157

Protein

rpsG

PMID:15690043[7]

Experiment(s):EBI-894157

Protein

rpsN

PMID:15690043[7]

Experiment(s):EBI-894157

Protein

rpsT

PMID:15690043[7]

Experiment(s):EBI-894157

Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

CompartmentDescriptionEvidenceSourceNotes

Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Sequence

at EcoCyc

MQENISVTDS YSTGNAAQAM LEKLLQIYDV KTLVAQLNGV GENHWSAAIL KRALANDSAW
HRLSEKEFAH LQTLLPKPPA HHPHYAFRFI DLFAGIGGIR RGFESIGGQC VFTSEWNKHA
VRTYKANHYC DPATHHFNED IRDITLSHKE GVSDEAAAEH IRQHIPEHDV LLAGFPCQPF
SLAGVSKKNS LGRAHGFACD TQGTLFFDVV RIIDARRPAM FVLENVKNLK SHDQGKTFRI
IMQTLDELGY DVADAEDNGP DDPKIIDGKH FLPQHRERIV LVGFRRDLNL KADFTLRDIS
ECFPAQRVTL AQLLDPMVEA KYILTPVLWK YLYRYAKKHQ ARGNGFGYGM VYPNNPQSVT
RTLSARYYKD GAEILIDRGW DMATGEKDFD DPLNQQHRPR RLTPRECARL MGFEAPGEAK
FRIPVSDTQA YRQFGNSVVV PVFAAVAKLL EPKIKQAVAL RQQEAQHGRR SR
Length

472

Mol. Wt

53.465 kDa

pI

8.7 (calculated)

Extinction coefficient

49,850 - 50,600 (calc based on 15 Y, 5 W, and 6 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

TypeResiduesDescriptionNotesReferences


Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures
Models

View models at:

Structure figures

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource typeSourceNotes/Reference

Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

DatabaseAccessionNotes

EcoCyc (EcoliWiki Page)

EcoCyc:EG10211-MONOMER

UniProt (EcoliWiki Page)

UniProt:P0AED9

PFAM (EcoliWiki Page)

PFAM:PF00145

RefSeq (EcoliWiki Page)

RefSeq:NP_416470


Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. 5.0 5.1 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  6. 6.0 6.1 6.2 6.3 6.4 EcoCyc (release 13.0; 2009) Keseler, IM et al. (2009) Nucleic Acids Res. 37(Database issue):D464-70
  7. 7.00 7.01 7.02 7.03 7.04 7.05 7.06 7.07 7.08 7.09 7.10 Butland G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433: 531-7 PubMed EcoliWiki page
  8. 8.0 8.1 8.2 8.3 8.4 8.5 8.6 Arifuzzaman M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res 16: 686-91 PubMed EcoliWiki page

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