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deaD:Quickview

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Standard Name

deaD

Gene Synonym(s)

ECK3150, b3162, JW5531, mssB, rhlD[1], csdA, rhlD

Product Desc.

CsdA, DEAD-box RNA helicase[2][3]

Translation factor W2, putative RNA helix-destabilizer; facilitates translation of mRNAs with 5' secondary structures; multicopy suppressor of rpsB(Ts) mutations[4]

Product Synonyms(s)

ATP-dependent RNA helicase[1], B3162[2][1], RhlD[2][1], MssB[2][1], DeaD[2][1] , csdA, ECK3150, JW5531, mssB, rhlD, b3162

Function from GO

Biological Process

Molecular Function

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): deaD[2]

Regulation/Activity
Quick Links

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Notes

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Mechanism of DeaD 50S biogenesis differs from that for SrmB 50S biogenesis. stabilizes exposed mRNA, possibly by protecting or destabilizing secondary structure of RNase E sites. Cold shock-inducible; acid-inducible.[4]



References

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  1. 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.