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deoR:Quickview
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| Standard Name |
deoR |
|---|---|
| Gene Synonym(s) |
ECK0830, b0840, JW0824, nucR[1] |
| Product Desc. |
DeoR transcriptional repressor[2][3] Repressor for deo operon, nupG and tsx; binds deoxyribose-5-phosphate inducer[4] |
| Product Synonyms(s) |
DNA-binding transcriptional repressor[1], B0840[2][1], NucR[2][1], DeoR[2][1], transcriptional repressor for deo operon, tsx, nupG[2][1] |
| Function from GO | |
| Knock-Out Phenotype | |
| Regulation/Expression | |
| Regulation/Activity | |
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Notes
The deoR gene is found immediately upstream of the operon. DeoR encodes a repressor protein that negatively regulates the expression of the operon at the level of transcription. A deoR-deficient mutant has a high level of deoxyriboaldolase and pyrimidine nucleoside phosphorylase. [5] In deoR mutations, the repressor is absent and the colonies of the mutants grow more rapidly (Munch-Peterson, et al, Eur. J. Biochem 27: 208-215 (1972)).
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
- ↑ Zeng X & Saxild HH (1999) Identification and characterization of a DeoR-specific operator sequence essential for induction of dra-nupC-pdp operon expression in Bacillus subtilis. J Bacteriol 181: 1719-27 PubMed EcoliWiki page
