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References Suggestions

Standard Name


Gene Synonym(s)

ECK3629, b3639, JW5642, dnaS, coaBC[1], coaBC

Product Desc.


Coenzyme A biosynthesis, bifunctional enzyme; phosphopantothenoylcysteine decarboxylase (N) and phosphopantothenoylcysteine synthase (C)[4]

Product Synonyms(s)

fused 4'-phosphopantothenoylcysteine decarboxylase[1], phosphopantothenoylcysteine synthetase, FMN-binding[1], B3639[2][1], DnaS[2][1], Dfp[2][1] , coaBC, ECK3629, JW5642, b3639

Function from GO
Knock-Out Phenotype

transcription unit(s):

Quick Links

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Dfp was originally identified as a flavoprotein affecting DNA synthesis and pantothenate metabolism. The N-terminal domain catalyzes the decarboxylation of (R)-4'-phospho-N-pantothenoylcysteine to 4'-phosphopantetheine.[4]


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  1. 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.