dnaX:Quickview

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Standard Name	dnaX
Gene Synonym(s)	ECK0464, b0470, JW0459, dnaZ^[1]
Product Desc.	DNA polymerase III, gamma subunit^[2]^[3] DNA polymerase III, tau subunit^[2]^[3] Component of DNA polymerase III, preinitiation complex^[3]; DNA polymerase III, τ subunit dimer^[3] DNA polymerase III, holoenzyme^[3] DNA polymerase III holoenzyme, tau and gamma ATPase subunits; gamma chain (aa 1-431) is main subunit of the clamp loader complex^[4]
Product Synonyms(s)	DNA polymerase III/DNA elongation factor III, tau and gamma subunits^[1], DnaZ^[2]^[1], B0470^[2]^[1]
Function from GO	Molecular Function GO:0005515 protein binding (IPI) GO:0017111 nucleoside-triphosphatase activity (IDA) GO:0016887 ATPase activity (IDA) GO:0030337 DNA polymerase processivity factor activity (IDA) Biological Process GO:0006261 DNA-dependent DNA replication (IDA) GO:0006260 DNA replication (IMP) Cellular Component GO:0043846 DNA polymerase III, DnaX complex (IDA)
Knock-Out Phenotype
Regulation/Expression	transcription unit(s): dnaX^[2]
Regulation/Activity
Quick Links	DNA display Protein display Pubmed(dnaX) Textpresso(dnaX)
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The tau chain is the full length protein. The gamma chain is formed by programmed ribosomal frameshifting at codon 431 to a premature stop codon.^[4]

References

↑ ^1.0 ^1.1 ^1.2 ^1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
↑ ^2.0 ^2.1 ^2.2 ^2.3 ^2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ ^3.0 ^3.1 ^3.2 ^3.3 ^3.4 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ ^4.0 ^4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.