fdnI:Gene Product(s)

Standard name	FdnI
Synonyms	formate dehydrogenase-N, cytochrome B556 (gamma) subunit, nitrate-inducible^[1], B1476^[2]^[1], FdnI^[2]^[1]
Product description	formate dehydrogenase N, γ subunit^[2]^[3]; Component of trimer complex of formate dehydrogenase-N α, β and γ subunits^[2]^[3]; formate dehydrogenase-N^[2]^[3] Formate dehydrogenase-N, cytochrome subunit, anaerobic^[4]
EC number (for enzymes)
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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier	GO ID	GO term name	Reference(s)	Evidence Code	with/from	Aspect	Notes	Status
	GO:0045333	cellular respiration	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR006471	P	Seeded from EcoCyc 12.5 ^[5]	complete
	GO:0009326	formate dehydrogenase complex	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR006471	C	Seeded from EcoCyc 12.5 ^[5]	complete
	GO:0008863	formate dehydrogenase activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR006471	F	Seeded from EcoCyc 12.5 ^[5]	complete
	GO:0006810	transport	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0813	P	Seeded from EcoCyc ^[6]	complete
	GO:0005506	iron ion binding	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0408	F	Seeded from EcoCyc ^[6]	complete
	GO:0008863	formate dehydrogenase activity	PMID:11752799^[7]	IDA: Inferred from Direct Assay		F	Seeded from EcoCyc 12.5 ^[5]	complete
	GO:0009055	electron carrier activity	PMID:1099094^[8]	IDA: Inferred from Direct Assay		F	Seeded from EcoCyc ^[6]	complete
	GO:0009061	anaerobic respiration	PMID:1099093^[9]	IDA: Inferred from Direct Assay		P	Seeded from EcoCyc ^[6]	complete
	GO:0009326	formate dehydrogenase complex	PMID:11752799^[7]	IDA: Inferred from Direct Assay		C	Seeded from EcoCyc 12.5 ^[5]	complete
	GO:0016021	integral to membrane	PMID:6755185^[10]	IDA: Inferred from Direct Assay		C	Seeded from EcoCyc 12.5 ^[5]	complete
	GO:0017004	cytochrome complex assembly	PMID:1099093^[9]	IDA: Inferred from Direct Assay		P	Seeded from EcoCyc ^[6]	complete
	GO:0045333	cellular respiration	PMID:5996^[11]	IDA: Inferred from Direct Assay		P	Seeded from EcoCyc 12.5 ^[5]	complete
	GO:0009053	electron donor activity				F	Seeded from EcoCyc 11.1^[3].	required fields missing
	GO:0005886	plasma membrane	GO_REF:0000004 GO_REF:0000004 GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_KW:KW-0997 SP_KW:KW-1003 SP_SL:SL-0037	C	Seeded from EcoCyc ^[6]	complete
	GO:0016020	membrane	GO_REF:0000002 GO_REF:0000004	IEA: Inferred from Electronic Annotation	InterPro:IPR016174 SP_KW:KW-0472	C	Seeded from EcoCyc ^[6]	complete
	GO:0022900	electron transport chain	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0249	P	Seeded from EcoCyc ^[6]	complete
	GO:0022904	respiratory electron transport chain	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR016174	P	Seeded from EcoCyc ^[6]	complete
	GO:0046872	metal ion binding	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0479	F	Seeded from EcoCyc ^[6]	complete
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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type	Partner	Notes
Protein	Subunits of trimer complex of formate dehydrogenase-N α, β and γ subunits	could be indirect
Protein	Subunits of formate dehydrogenase-N	could be indirect
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment	Description	Evidence	Source
plasma membrane	C-terminus localized in the cytoplasm with 4 predicted transmembrane domains	Daley et al. (2005) ^[12]
plasma membrane			From EcoCyc^[3]
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Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Sequence	at EcoCyc MSKSKMIVRT KFIDRACHWT VVICFFLVAL SGISFFFPTL QWLTQTFGTP QMGRILHPFF GIAIFVALMF MFVRFVHHNI PDKKDIPWLL NIVEVLKGNE HKVADVGKYN AGQKMMFWSI MSMIFVLLVT GVIIWRPYFA QYFPMQVVRY SLLIHAAAGI ILIHAILIHM YMAFWVKGSI KGMIEGKVSR RWAKKHHPRW YREIEKAEAK KESEEGI
Length	217
Mol. Wt	25.368 kDa
pI	10.3 (calculated)
Extinction coefficient	52,940 - 53,190 (calc based on 6 Y, 8 W, and 2 C residues)
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Domains/Motifs/Modification Sites

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Type	Residues	Description	Notes	References
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Click the image to view raw output from TMHMM.

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

Representative Escherichia coli structure:
1KQF|C
1-217 of 217 residues (E-value: 3e-118) (Percent Identity: 100.00)
View the PDB Table for fdnI

Models

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Structure figures

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type	Source	Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database	Accession	Notes
EcoCyc (EcoliWiki Page)	EcoCyc:FDNI-MONOMER
SwissModel (EcoliWiki Page)	SwissModel:P0AEK7
UniProt (EcoliWiki Page)	UniProt:P0AEK7
RefSeq (EcoliWiki Page)	RefSeq:NP_415993
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Notes

Links

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Name	URL	Comments
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References

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See Help:References for how to manage references in EcoliWiki.

↑ ^1.0 ^1.1 ^1.2 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
↑ ^2.0 ^2.1 ^2.2 ^2.3 ^2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ ^3.0 ^3.1 ^3.2 ^3.3 ^3.4 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
↑ ^5.0 ^5.1 ^5.2 ^5.3 ^5.4 ^5.5 ^5.6 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ ^6.0 ^6.1 ^6.2 ^6.3 ^6.4 ^6.5 ^6.6 ^6.7 ^6.8 ^6.9 EcoCyc (release 13.0; 2009) Keseler, IM et al. (2009) Nucleic Acids Res. 37(Database issue):D464-70
↑ ^7.0 ^7.1 Jormakka M et al. (2002) Purification and crystallization of the respiratory complex formate dehydrogenase-N from Escherichia coli. Acta Crystallogr D Biol Crystallogr 58: 160-2 PubMed EcoliWiki page
↑ Boonstra J et al. (1975) Anaerobic transport in Escherichia coli membrane vesicles. J Biol Chem 250: 6792-8 PubMed EcoliWiki page
↑ ^9.0 ^9.1 Enoch HG & Lester RL (1975) The purification and properties of formate dehydrogenase and nitrate reductase from Escherichia coli. J Biol Chem 250: 6693-705 PubMed EcoliWiki page
↑ Enoch HG & Lester RL (1982) Formate dehydrogenase from Escherichia coli. Methods Enzymol 89 Pt D: 537-43 PubMed EcoliWiki page
↑ Garland PB et al. (1975) Proton translocation and the respiratory nitrate reductase of Escherichia coli. Biochem J 152: 547-59 PubMed EcoliWiki page
↑ Daley DO et al. (2005) Global topology analysis of the Escherichia coli inner membrane proteome. Science 308: 1321-3 PubMed EcoliWiki page

fdnI:Gene Product(s)

From EcoliWiki

Nomenclature

Notes

Function

Notes

Localization

Notes

Structure and Physical Properties

Structure figures

Notes

Gene Product Resources

Notes

Accessions in Other Databases

Notes

Links

References

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