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fixA:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

FixA

Synonyms

predicted electron transfer flavoprotein subunit, ETFP adenine nucleotide-binding domain[1], B0041[2][1], YaaQ[2][1], FixA[2][1]

Product description

probable flavoprotein subunit required for anaerobic carnitine metabolism[2][3]

Required for anaerobic carnitine reduction; similar to Rhizobium fix gene[4]

EC number (for enzymes)


Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

QualifierGO IDGO term nameReference(s)Evidence Codewith/fromAspectNotesStatus
GO:0009437

carnitine metabolic process

GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_01055

P

Seeded from EcoCyc [5]

complete

GO:0009055

electron carrier activity

GO_REF:0000002
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000049
InterPro:IPR012255

F

Seeded from EcoCyc [5]

complete

GO:0006810

transport

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0813

P

Seeded from EcoCyc [5]

complete

GO:0022900

electron transport chain

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0249

P

Seeded from EcoCyc [5]

complete

GO:0055114

oxidation reduction

GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_01055

P

Seeded from EcoCyc [5]

complete

GO:0009437

carnitine metabolic process

PMID:12081978[6]

IMP: Inferred from Mutant Phenotype

P

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner TypePartnerNotesReferencesEvidence

Protein

dnaK

PMID:16606699[7]

Experiment(s):EBI-1135409

Protein

ulaF

PMID:16606699[7]

Experiment(s):EBI-1135409

Protein

nadE

PMID:16606699[7]

Experiment(s):EBI-1135409

Protein

ttdA

PMID:16606699[7]

Experiment(s):EBI-1135409

Protein

rpsC

PMID:16606699[7]

Experiment(s):EBI-1135409

Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

CompartmentDescriptionEvidenceSourceNotes

Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Sequence

at EcoCyc

MNDVSFMISG DAMKIITCYK CVPDEQDIAV NNADGSLDFS KADAKISQYD LNAIEAACQL
KQQAAEAQVT ALSVGGKALT NAKGRKDVLS RGPDELIVVI DDQFEQALPQ QTASALAAAA
QKAGFDLILC GDGSSDLYAQ QVGLLVGEIL NIPAVNGVSK IISLTADTLT VERELEDETE
TLSIPLPAVV AVSTDINSPQ IPSMKAILGA AKKPVQVWSA ADIGFNAEAA WSEQQVAAPK
QRERQRIVIE GDGEEQIAAF AENLRKVI
Length

268

Mol. Wt

28.412 kDa

pI

4.2 (calculated)

Extinction coefficient

15,470 - 15,970 (calc based on 3 Y, 2 W, and 4 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

TypeResiduesDescriptionNotesReferences


Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures
Models

View models at:

Structure figures

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource typeSourceNotes/Reference

Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

DatabaseAccessionNotes

EcoCyc (EcoliWiki Page)

EcoCyc:EG11562-MONOMER

UniProt (EcoliWiki Page)

UniProt:P60566

PFAM (EcoliWiki Page)

PFAM:PF01012

RefSeq (EcoliWiki Page)

RefSeq:NP_414583


Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. 5.0 5.1 5.2 5.3 5.4 EcoCyc (release 13.0; 2009) Keseler, IM et al. (2009) Nucleic Acids Res. 37(Database issue):D464-70
  6. Walt A & Kahn ML (2002) The fixA and fixB genes are necessary for anaerobic carnitine reduction in Escherichia coli. J Bacteriol 184: 4044-7 PubMed EcoliWiki page
  7. 7.0 7.1 7.2 7.3 7.4 Arifuzzaman M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res 16: 686-91 PubMed EcoliWiki page

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