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fixB:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

FixB

Synonyms

predicted electron transfer flavoprotein, NAD/FAD-binding domain and ETFP adenine nucleotide-binding domain-like[1], B0042[2][1], YaaR[2][1], FixB[2][1]

Product description

probable flavoprotein subunit required for anaerobic carnitine metabolism[2][3]

Required for anaerobic carnitine reduction; similar to Rhizobium fix gene[4]

EC number (for enzymes)


Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

QualifierGO IDGO term nameReference(s)Evidence Codewith/fromAspectNotesStatus
GO:0050660

FAD binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001308

F

Seeded from EcoCyc [5]

complete

GO:0009437

carnitine metabolic process

GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_01056

P

Seeded from EcoCyc [5]

complete

GO:0009055

electron carrier activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001308

F

Seeded from EcoCyc [5]

complete

GO:0006810

transport

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0813

P

Seeded from EcoCyc [5]

complete

GO:0022900

electron transport chain

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0249

P

Seeded from EcoCyc [5]

complete

GO:0055114

oxidation reduction

GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_01056

P

Seeded from EcoCyc [5]

complete

GO:0009437

carnitine metabolic process

PMID:12081978[6]

IMP: Inferred from Mutant Phenotype

P

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner TypePartnerNotesReferencesEvidence

Protein

groL

PMID:16606699[7]

Experiment(s):EBI-1135416

Protein

pta

PMID:16606699[7]

Experiment(s):EBI-1135416

Protein

fhlA

PMID:16606699[7]

Experiment(s):EBI-1135416

Protein

dnaK

PMID:16606699[7]

Experiment(s):EBI-1135416

Protein

rplJ

PMID:16606699[7]

Experiment(s):EBI-1135416

Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

CompartmentDescriptionEvidenceSourceNotes

Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Sequence

at EcoCyc

MNTFSQVWVF SDTPSRLPEL MNGAQALANQ INTFVLNDAD GAQAIQLGAN HVWKLNGKPD
DRMIEDYAGV MADTIRQHGA DGLVLLPNTR RGKLLAAKLG YRLKAAVSND ASTVSVQDGK
ATVKHMVYGG LAIGEERIAT PYAVLTISSG TFDAAQPDAS RTGETHTVEW QAPAVAITRT
ATQARQSNSV DLDKARLVVS VGRGIGSKEN IALAEQLCKA IGAELACSRP VAENEKWMEH
ERYVGISNLM LKPELYLAVG ISGQIQHMVG ANASQTIFAI NKDKNAPIFQ YADYGIVGDA
VKILPALTAA LAR
Length

313

Mol. Wt

33.513 kDa

pI

7.2 (calculated)

Extinction coefficient

33,920 - 34,170 (calc based on 8 Y, 4 W, and 2 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

TypeResiduesDescriptionNotesReferences


Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures
Models

View models at:

Structure figures

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource typeSourceNotes/Reference

Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

DatabaseAccessionNotes

EcoCyc (EcoliWiki Page)

EcoCyc:EG11563-MONOMER

UniProt (EcoliWiki Page)

UniProt:P31574

PFAM (EcoliWiki Page)

PFAM:PF00766

RefSeq (EcoliWiki Page)

RefSeq:NP_414584


Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. 5.0 5.1 5.2 5.3 5.4 5.5 EcoCyc (release 13.0; 2009) Keseler, IM et al. (2009) Nucleic Acids Res. 37(Database issue):D464-70
  6. Walt A & Kahn ML (2002) The fixA and fixB genes are necessary for anaerobic carnitine reduction in Escherichia coli. J Bacteriol 184: 4044-7 PubMed EcoliWiki page
  7. 7.0 7.1 7.2 7.3 7.4 Arifuzzaman M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res 16: 686-91 PubMed EcoliWiki page

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