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fixC:Gene Product(s)
From EcoliWiki
| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| Nomenclature | Function | Interactions | Localization | Sequence | Domains | Structure | Resources | Accessions | Links | References | Suggestions |
Nomenclature
See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.
| Standard name |
FixC |
|---|---|
| Synonyms |
predicted oxidoreductase with FAD/NAD(P)-binding domain[1], B0043[2][1], YaaS[2][1], FixC[2][1] |
| Product description |
flavoprotein (electron transport), possibly involved in anaerobic carnitine metabolism[2][3] Related to carnitine metabolism; similarity to Rhizobium fix gene[4] |
| EC number (for enzymes) |
|
| edit table |
Notes
Function
Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.
| Qualifier | GO ID | GO term name | Reference(s) | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0016491 |
oxidoreductase activity |
IEA: Inferred from Electronic Annotation |
InterPro:IPR001100 |
F |
Seeded from EcoCyc 12.5 [5] |
complete | ||
| GO:0006810 |
transport |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc [6] |
complete | |||
| GO:0042413 |
carnitine catabolic process |
P |
Seeded from EcoCyc 11.1[3]. |
required fields missing | ||||
| GO:0008152 |
metabolic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc [6] |
complete | |||
| GO:0022900 |
electron transport chain |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc [6] |
complete | |||
| GO:0055114 |
oxidation reduction |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc [6] |
complete | |||
| GO:0050660 |
FAD binding |
ISA: Inferred from Sequence Alignment |
F |
complete | ||||
| GO:0051536 |
iron-sulfur cluster binding |
ISA: Inferred from Sequence Alignment |
F |
complete | ||||
| GO:0004174 |
electron-transferring-flavoprotein dehydrogenase activity |
ISA: Inferred from Sequence Alignment |
F |
complete | ||||
| GO:0009437 |
carnitine metabolic process |
IEP: Inferred from Expression Pattern |
P |
The fixABCX operon is adjacent to and regulated similarity to the cai operon, which is necessary for carnitine metabolism [10]. |
complete | |||
| edit table |
Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.
| Partner Type | Partner | Notes | References | Evidence |
|---|---|---|---|---|
|
Protein |
Experiment(s):EBI-1135423 | |||
|
Protein |
Experiment(s):EBI-1135423 | |||
|
Protein |
Experiment(s):EBI-1135423 | |||
|
Protein |
Experiment(s):EBI-1135423 | |||
|
Protein |
Experiment(s):EBI-1135423 | |||
|
Protein |
Experiment(s):EBI-1135423 | |||
|
Protein |
Experiment(s):EBI-1135423 | |||
| edit table |
Notes
Localization
See Help:Product_localization for how to add or edit information in this section of EcoliWiki.
| Compartment | Description | Evidence | Source | Notes |
|---|---|---|---|---|
| edit table |
Notes
Structure and Physical Properties
Physical Properties
See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.
| Sequence |
MSEDIFDAII VGAGLAGSVA ALVLAREGAQ VLVIERGNSA GAKNVTGGRL YAHSLEHIIP GFADSAPVER LITHEKLAFM TEKSAMTMDY CNGDETSPSQ RSYSVLRSKF DAWLMEQAEE AGAQLITGIR VDNLVQRDGK VVGVEADGDV IEAKTVILAD GVNSILAEKL GMAKRVKPTD VAVGVKELIE LPKSVIEDRF QLQGNQGAAC LFAGSPTDGL MGGGFLYTNE NTLSLGLVCG LHHLHDAKKS VPQMLEDFKQ HPAVAPLIAG GKLVEYSAHV VPEAGINMLP ELVGDGVLIA GDAAGMCMNL GFTIRGMDLA IAAGEAAAKT VLSAMKSDDF SKQKLAEYRQ HLESGPLRDM RMYQKLPAFL DNPRMFSGYP ELAVGVARDL FTIDGSAPEL MRKKILRHGK KVGFINLIKD GMKGVTVL |
|---|---|
| Length |
428 |
| Mol. Wt |
45.703 kDa |
| pI |
5.9 (calculated) |
| Extinction coefficient |
17,420 - 17,920 (calc based on 8 Y, 1 W, and 4 C residues) |
| edit table |
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See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.
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Structure
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Structure figures
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| Resource type | Source | Notes/Reference |
|---|---|---|
| edit table |
Notes
Accessions in Other Databases
See Help:Gene_accessions for help with entering information into the Gene Accessions table.
| Database | Accession | Notes |
|---|---|---|
|
| ||
| edit table |
Notes
Links
| Name | URL | Comments |
|---|---|---|
| edit table |
References
See Help:References for how to manage references in EcoliWiki.
- ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
- ↑ EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 6.0 6.1 6.2 6.3 EcoCyc (release 13.0; 2009) Keseler, IM et al. (2009) Nucleic Acids Res. 37(Database issue):D464-70
- ↑ 7.0 7.1 7.2 Beckmann JD & Frerman FE (1985) Electron-transfer flavoprotein-ubiquinone oxidoreductase from pig liver: purification and molecular, redox, and catalytic properties. Biochemistry 24: 3913-21 PubMed EcoliWiki page
- ↑ 8.0 8.1 8.2 Zhang J et al. (2006) Structure of electron transfer flavoprotein-ubiquinone oxidoreductase and electron transfer to the mitochondrial ubiquinone pool. Proc Natl Acad Sci U S A 103: 16212-7 PubMed EcoliWiki page
- ↑ Eichler K et al. (1995) The fix Escherichia coli region contains four genes related to carnitine metabolism. J Basic Microbiol 35: 217-27 PubMed EcoliWiki page
- ↑ Eichler K et al. (1994) Molecular characterization of the cai operon necessary for carnitine metabolism in Escherichia coli. Mol Microbiol 13: 775-86 PubMed EcoliWiki page
- ↑ 11.0 11.1 11.2 11.3 11.4 11.5 11.6 Arifuzzaman M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res 16: 686-91 PubMed EcoliWiki page
