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fmt:Gene Product(s)

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

Fmt

Synonyms

10-formyltetrahydrofolate:L-methionyl-tRNA(fMet) N-formyltransferase[1], B3288[2][1], Ftm[2][1], YhdD[2][1], Fmt[2][1]

Product description

10-formyltetrahydrofolate:L-methionyl-tRNA(fMet) N-formyltransferase[2][3]

Methionyl-tRNA formyltransferase[4]

EC number (for enzymes)

Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

QualifierGO IDGO term nameReference(s)Evidence Codewith/fromAspectNotesStatus
GO:0016742

hydroxymethyl-, formyl- and related transferase activity

GO_REF:0000002
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002376
InterPro:IPR005793

F

Seeded from EcoCyc [5]

complete

GO:0016740

transferase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0808

F

Seeded from EcoCyc [5]

complete

GO:0009058

biosynthetic process

GO_REF:0000002
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002376
InterPro:IPR005793

P

Seeded from EcoCyc [5]

complete

GO:0008168

methyltransferase activity

GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR001555
SP_KW:KW-0489

F

Seeded from EcoCyc [5]

complete

GO:0006412

translation

GO_REF:0000002
GO_REF:0000002
GO_REF:0000004
GO_REF:0000020

IEA: Inferred from Electronic Annotation

InterPro:IPR001555
InterPro:IPR005794
SP_KW:KW-0648
HAMAP:MF_00182

P

Seeded from EcoCyc 12.5 [6]

complete

GO:0004479

methionyl-tRNA formyltransferase activity

GO_REF:0000002
GO_REF:0000003
GO_REF:0000020

IEA: Inferred from Electronic Annotation

InterPro:IPR005794
EC:2.1.2.9
HAMAP:MF_00182

F

Seeded from EcoCyc 12.5 [6]

complete

GO:0003824

catalytic activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011034

F

Seeded from EcoCyc [5]

complete

GO:0005737

cytoplasm

C

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0009451

RNA modification

P

Seeded from EcoCyc 11.1[3].

required fields missing

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner TypePartnerNotesReferencesEvidence

Protein

rfaP

PMID:16606699[7]

Experiment(s):EBI-1145369

Protein

rpsG

PMID:16606699[7]

Experiment(s):EBI-1145369

Protein

rplQ

PMID:16606699[7]

Experiment(s):EBI-1145369

Protein

rplA

PMID:16606699[7]

Experiment(s):EBI-1145369

Protein

rpsM

PMID:16606699[7]

Experiment(s):EBI-1145369

Protein

ydfK

PMID:16606699[7]

Experiment(s):EBI-1145369

Protein

rplD

PMID:16606699[7]

Experiment(s):EBI-1145369

Protein

rpsI

PMID:16606699[7]

Experiment(s):EBI-1145369

Protein

rpsD

PMID:16606699[7]

Experiment(s):EBI-1145369, EBI-1145434

Protein

ynaE

PMID:16606699[7]

Experiment(s):EBI-1145369

Protein

rplI

PMID:16606699[7]

Experiment(s):EBI-1145369

Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

CompartmentDescriptionEvidenceSourceNotes

cytoplasm

From EcoCyc[3]


Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Sequence

at EcoCyc

MSESLRIIFA GTPDFAARHL DALLSSGHNV VGVFTQPDRP AGRGKKLMPS PVKVLAEEKG
LPVFQPVSLR PQENQQLVAE LQADVMVVVA YGLILPKAVL EMPRLGCINV HGSLLPRWRG
AAPIQRSLWA GDAETGVTIM QMDVGLDTGD MLYKLSCPIT AEDTSGTLYD KLAELGPQGL
ITTLKQLADG TAKPEVQDET LVTYAEKLSK EEARIDWSLS AAQLERCIRA FNPWPMSWLE
IEGQPVKVWK ASVIDTATNA APGTILEANK QGIQVATGDG ILNLLSLQPA GKKAMSAQDL
LNSRREWFVP GNRLV
Length

315

Mol. Wt

34.168 kDa

pI

5.5 (calculated)

Extinction coefficient

44,460 - 44,835 (calc based on 4 Y, 7 W, and 3 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

TypeResiduesDescriptionNotesReferences

Initiator Methionine

1

Removed

UniProt:P23882



rectanglemotifs

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures
Models

View models at:

Structure figures

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource typeSourceNotes/Reference

Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

DatabaseAccessionNotes

EcoCyc (EcoliWiki Page)

EcoCyc:EG11268-MONOMER

UniProt (EcoliWiki Page)

UniProt:P23882

PFAM (EcoliWiki Page)

PFAM:PF00551

RefSeq (EcoliWiki Page)

RefSeq:NP_417746


Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 3.2 3.3 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. 5.0 5.1 5.2 5.3 5.4 EcoCyc (release 13.0; 2009) Keseler, IM et al. (2009) Nucleic Acids Res. 37(Database issue):D464-70
  6. 6.0 6.1 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  7. 7.00 7.01 7.02 7.03 7.04 7.05 7.06 7.07 7.08 7.09 7.10 Arifuzzaman M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res 16: 686-91 PubMed EcoliWiki page

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