galK:Gene Product(s) - EcoliWiki
EcoliHub logo

E. coli is indeed the coolest thing on the planet - Carl Zimmer

galK:Gene Product(s)

From EcoliWiki

Jump to: navigation, search


Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

Standard name

GalK product

Synonyms

galactokinase product[1], B0757 product[2][1], GalA product[2][1], GalK product[2][1], ATP:D-galactose 1-phosphotransferase product[2][1]

Product description

GALACTOKIN-MONOMER[2][3]

EC number (for enzymes)
edit table

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Notes

Function

[back to top]


Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

QualifierGO IDGO term nameReference(s)Evidence Codewith/fromAspectNotesStatus
GO:0000166

nucleotide binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0547

F

Seeded from EcoCyc 12.5 [4]

complete

GO:0004335

galactokinase activity

GO_REF:0000002
GO_REF:0000003
GO_REF:0000020

IEA: Inferred from Electronic Annotation

InterPro:IPR000705
EC:2.7.1.6
HAMAP:MF_00246

F

Seeded from EcoCyc 12.5 [4]

complete

GO:0005524

ATP binding

GO_REF:0000002
GO_REF:0000002
GO_REF:0000002
GO_REF:0000002
GO_REF:0000004
GO_REF:0000020

IEA: Inferred from Electronic Annotation

InterPro:IPR000705
InterPro:IPR006203
InterPro:IPR006204
InterPro:IPR006206
SP_KW:KW-0067
HAMAP:MF_00246

F

Seeded from EcoCyc 12.5 [4]

complete

GO:0005737

cytoplasm

GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR006206
SP_KW:KW-0963

C

Seeded from EcoCyc 12.5 [4]

complete

GO:0005975

carbohydrate metabolic process

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0119

P

Seeded from EcoCyc 12.5 [4]

complete

GO:0006012

galactose metabolic process

GO_REF:0000002
GO_REF:0000004
GO_REF:0000020

IEA: Inferred from Electronic Annotation

InterPro:IPR000705
SP_KW:KW-0299
HAMAP:MF_00246

P

Seeded from EcoCyc 12.5 [4]

complete

GO:0008152

metabolic process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006206

P

Seeded from EcoCyc 12.5 [4]

complete

GO:0016301

kinase activity

GO_REF:0000002
GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR006204
InterPro:IPR006206
SP_KW:KW-0418

F

Seeded from EcoCyc 12.5 [4]

complete

GO:0016310

phosphorylation

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006204

P

Seeded from EcoCyc 12.5 [4]

complete

GO:0016740

transferase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0808

F

Seeded from EcoCyc 12.5 [4]

complete

GO:0016773

phosphotransferase activity, alcohol group as acceptor

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006206

F

Seeded from EcoCyc 12.5 [4]

complete

GO:0046835

carbohydrate phosphorylation

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000705

P

Seeded from EcoCyc 12.5 [4]

complete

GO:0006012

galactose metabolic process

PMID:13390972[5]

IMP: Inferred from Mutant Phenotype

P

Seeded from EcoCyc 11.1[3].

complete

Under review

GO:0009242

colanic acid biosynthetic process

P

Seeded from EcoCyc 11.1[3].

required field missing

GO:0016052

carbohydrate catabolic process

P

Seeded from EcoCyc 11.1[3].

required fields missing

Under review

GO:0009269

response to desiccation

P

Seeded from EcoCyc 11.1[3].

required field missing

Under review

GO:0042603

capsule

C

Seeded from EcoCyc 11.1[3].

required field missing

GO:0004335

galactokinase activity

PMID:13977183[6]

IDA: Inferred from Direct Assay

F

complete

GO:0004335

galactokinase activity

PMID:13390972[5]

IMP: Inferred from Mutant Phenotype

F

complete

GO:0016310

phosphorylation

PMID:13977183[6]

IDA: Inferred from Direct Assay

P

Seeded from EcoCyc 12.5 [4]

complete

GO:0016301

kinase activity

GO:0016301

IDA: Inferred from Direct Assay

F

Seeded from EcoCyc 12.5 [4]

complete

GO:0006012

galactose metabolic process

PMID:13914787[7]

IMP: Inferred from Mutant Phenotype

P

Seeded from EcoCyc 12.5 [4]

complete

GO:0005737

cytoplasm

C

required field missing

GO:0033499

galactose catabolic process via UDP-galactose

PMID:16590575[8]

IMP: Inferred from Mutant Phenotype

P

Enzyme assays on a variety of gal mutants.

complete

edit table

Interactions

Partner TypePartnerNotesReferences
edit table

See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Notes

Localization

CompartmentDescriptionEvidenceNotes
edit table

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Notes

Structure and Physical Properties

[back to top]


Physical Properties

Sequence

at EcoCyc

MSLKEKTQSL FANAFGYPAT HTIQAPGRVN LIGEHTDYND GFVLPCAIDY QTVISCAPRD
DRKVRVMAAD YENQLDEFSL DAPIVAHENY QWANYVRGVV KHLQLRNNSF GGVDMVISGN
VPQGAGLSSS ASLEVAVGTV LQQLYHLPLD GAQIALNGQE AENQFVGCNC GIMDQLISAL
GKKDHALLID CRSLGTKAVS MPKGVAVVII NSNFKRTLVG SEYNTRREQC ETGARFFQQP
ALRDVTIEEF NAVAHELDPI VAKRVRHILT ENARTVEAAS ALEQGDLKRM GELMAESHAS
MRDDFEITVP QIDTLVEIVK AVIGDKGGVR MTGGGFGGCI VALIPEELVP AVQQAVAEQY
EAKTGIKETF YVCKPSQGAG QC
Mol. Wt

41.44 kDa (calc) [2]

pI

5.52[2]

Extinction coefficient

20400 - 21525 (calc based on 10 Y, 1 W, and 9 C residues)

edit table

See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Domains/Motifs/Modification Sites

TypeResiduesDescriptionNotes
edit table

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Structure

Structures
  • Representative homolog:
    1S4E|A (Pyrococcus furiosus)
    5-351 of 382 residues (E-value: 1.4e-60) (Percent Identity: 37.05)
  • View all other structures.
Models

View models at:

edit table

See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Notes

Gene Product Resources

[back to top]


Resource typeSourceNotes/Reference

Purification protocol

PMID:13977183[6]

edit table

See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Notes

Accessions in Other Databases

[back to top]


DatabaseAccessionNotes

EcoCyc (EcoliWiki Page)

EcoCyc:GALACTOKIN-MONOMER

UniProt (EcoliWiki Page)

UniProt:P0A6T3

PFAM (EcoliWiki Page)

PFAM:PF00288

RefSeq (EcoliWiki Page)

RefSeq:NP_415278

ModBase (EcoliWiki Page)

ModBase:P0A6T3


edit table

See Help:Product_accessions for help entering or editing information in this section of EcoliWiki.

Notes

Links

[back to top]


NameURLComments
edit table

See Help:Links_table for how to enter or edit information in this section of EcoliWiki.



References

[back to top]


See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 3.2 3.3 3.4 3.5 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.00 4.01 4.02 4.03 4.04 4.05 4.06 4.07 4.08 4.09 4.10 4.11 4.12 4.13 4.14 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  5. 5.0 5.1 KURAHASHI K (1957) Enzyme formation in galactose-negative mutants of Escherichia coli. Science 125: 114-6 PubMed EcoliWiki page
  6. 6.0 6.1 6.2 SHERMAN JR & ADLER J (1963) Galactokinse from Escherichia coli. J Biol Chem 238: 873-8 PubMed EcoliWiki page
  7. SOFFER RL (1961) Enzymatic expression of genetic units of function concerned with galactose metabolism in Escherichia coli. J Bacteriol 82: 471-8 PubMed EcoliWiki page
  8. Kalckar HM et al. (1959) HEREDITARY DEFECTS IN GALACTOSE METABOLISM IN ESCHERICHIA COLI MUTANTS, I. DETERMINATION OF ENZYME ACTIVITIES. Proc Natl Acad Sci U S A 45: 1776-86 PubMed EcoliWiki page


Categories

[back to top]


Personal tools