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galK:Gene Product(s)
From EcoliWiki
| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| Nomenclature | Function | Interactions | Localization | Sequence | Domains | Structure | Resources | Accessions | Links | References | Suggestions |
Nomenclature
See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.
| Standard name |
GalK |
|---|---|
| Synonyms |
galactokinase[1], B0757[2][1], GalA[2][1], GalK[2][1], ATP:D-galactose 1-phosphotransferase[2][1] |
| Product description |
Galactokinase[3] |
| EC number (for enzymes) | |
| edit table |
Notes
Function
Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.
| Qualifier | GO ID | GO term name | Reference(s) | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000166 |
nucleotide binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc [4] |
complete | |||
| GO:0004335 |
galactokinase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc 12.5 [5] |
complete | |||
| GO:0005524 |
ATP binding |
GO_REF:0000002 |
IEA: Inferred from Electronic Annotation |
InterPro:IPR000705 |
F |
Seeded from EcoCyc 12.5 [5] |
complete | |
| GO:0005737 |
cytoplasm |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc 12.5 [5] |
complete | |||
| GO:0005975 |
carbohydrate metabolic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc [4] |
complete | |||
| GO:0006012 |
galactose metabolic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc 12.5 [5] |
complete | |||
| GO:0008152 |
metabolic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc [4] |
complete | |||
| GO:0016301 |
kinase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc [4] |
complete | |||
| GO:0016310 |
phosphorylation |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc [4] |
complete | |||
| GO:0016740 |
transferase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc [4] |
complete | |||
| GO:0016773 |
phosphotransferase activity, alcohol group as acceptor |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc [4] |
complete | |||
| GO:0046835 |
carbohydrate phosphorylation |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc [4] |
complete | |||
| GO:0006012 |
galactose metabolic process |
IMP: Inferred from Mutant Phenotype |
P |
Seeded from EcoCyc 11.1[7]. |
complete | |||
|
Under review | GO:0009242 |
colanic acid biosynthetic process |
P |
Seeded from EcoCyc 11.1[7]. |
required field missing | |||
| GO:0016052 |
carbohydrate catabolic process |
P |
Seeded from EcoCyc 11.1[7]. |
required fields missing | ||||
|
Under review | GO:0009269 |
response to desiccation |
P |
Seeded from EcoCyc 11.1[7]. |
required field missing | |||
|
Under review | GO:0042603 |
capsule |
C |
Seeded from EcoCyc 11.1[7]. |
required field missing | |||
| GO:0004335 |
galactokinase activity |
IDA: Inferred from Direct Assay |
F |
complete | ||||
| GO:0004335 |
galactokinase activity |
IMP: Inferred from Mutant Phenotype |
F |
complete | ||||
| GO:0016310 |
phosphorylation |
IDA: Inferred from Direct Assay |
P |
Seeded from EcoCyc 12.5 [5] |
complete | |||
| GO:0016301 |
kinase activity | GO:0016301 |
IDA: Inferred from Direct Assay |
F |
Seeded from EcoCyc 12.5 [5] |
complete | ||
| GO:0006012 |
galactose metabolic process |
IMP: Inferred from Mutant Phenotype |
P |
Seeded from EcoCyc 12.5 [5] |
complete | |||
| GO:0005737 |
cytoplasm |
IDA: Inferred from Direct Assay |
C |
complete | ||||
| GO:0033499 |
galactose catabolic process via UDP-galactose |
IMP: Inferred from Mutant Phenotype |
P |
Enzyme assays on a variety of gal mutants. |
complete | |||
| edit table |
Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.
| Partner Type | Partner | Notes | References | Evidence |
|---|---|---|---|---|
| edit table |
Notes
Localization
See Help:Product_localization for how to add or edit information in this section of EcoliWiki.
| Compartment | Description | Evidence | Source | Notes |
|---|---|---|---|---|
| edit table |
Notes
Structure and Physical Properties
Physical Properties
See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.
| Sequence |
MSLKEKTQSL FANAFGYPAT HTIQAPGRVN LIGEHTDYND GFVLPCAIDY QTVISCAPRD DRKVRVMAAD YENQLDEFSL DAPIVAHENY QWANYVRGVV KHLQLRNNSF GGVDMVISGN VPQGAGLSSS ASLEVAVGTV LQQLYHLPLD GAQIALNGQE AENQFVGCNC GIMDQLISAL GKKDHALLID CRSLGTKAVS MPKGVAVVII NSNFKRTLVG SEYNTRREQC ETGARFFQQP ALRDVTIEEF NAVAHELDPI VAKRVRHILT ENARTVEAAS ALEQGDLKRM GELMAESHAS MRDDFEITVP QIDTLVEIVK AVIGDKGGVR MTGGGFGGCI VALIPEELVP AVQQAVAEQY EAKTGIKETF YVCKPSQGAG QC |
|---|---|
| Length |
382 |
| Mol. Wt |
41.44 kDa |
| pI |
6.1 (calculated) |
| Extinction coefficient |
20,400 - 21,525 (calc based on 10 Y, 1 W, and 9 C residues) |
| edit table |
|
See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.
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Structure
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Structure figures
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| Resource type | Source | Notes/Reference |
|---|---|---|
|
Purification protocol | ||
| edit table |
Notes
Accessions in Other Databases
See Help:Gene_accessions for help with entering information into the Gene Accessions table.
| Database | Accession | Notes |
|---|---|---|
|
| ||
| edit table |
Notes
Links
| Name | URL | Comments |
|---|---|---|
| edit table |
References
See Help:References for how to manage references in EcoliWiki.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
- ↑ 4.0 4.1 4.2 4.3 4.4 4.5 4.6 4.7 EcoCyc (release 13.0; 2009) Keseler, IM et al. (2009) Nucleic Acids Res. 37(Database issue):D464-70
- ↑ 5.0 5.1 5.2 5.3 5.4 5.5 5.6 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 6.0 6.1 KURAHASHI K (1957) Enzyme formation in galactose-negative mutants of Escherichia coli. Science 125: 114-6 PubMed EcoliWiki page
- ↑ 7.0 7.1 7.2 7.3 7.4 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 8.0 8.1 8.2 SHERMAN JR & ADLER J (1963) Galactokinse from Escherichia coli. J Biol Chem 238: 873-8 PubMed EcoliWiki page
- ↑ SOFFER RL (1961) Enzymatic expression of genetic units of function concerned with galactose metabolism in Escherichia coli. J Bacteriol 82: 471-8 PubMed EcoliWiki page
- ↑ Wilson DB & Hogness DS (1969) The enzymes of the galactose operon in Escherichia coli. 3. The size and composition of galactokinase. J Biol Chem 244: 2137-42 PubMed EcoliWiki page
- ↑ Kalckar HM et al. (1959) HEREDITARY DEFECTS IN GALACTOSE METABOLISM IN ESCHERICHIA COLI MUTANTS, I. DETERMINATION OF ENZYME ACTIVITIES. Proc Natl Acad Sci U S A 45: 1776-86 PubMed EcoliWiki page
