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grpE:Gene Product(s)
From EcoliWiki
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| Nomenclature | Function | Interactions | Localization | Sequence | Domains | Structure | Resources | Accessions | Links | References | Suggestions |
Nomenclature
See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.
| Standard name |
GrpE |
|---|---|
| Synonyms | |
| Product description |
phage lambda replication; host DNA synthesis; heat shock protein; protein repair[2][3]; Component of DnaJ/DnaK/GrpE[2][3] Nucleotide exchange factor for the DnaKJ chaperone; heat shock protein; mutant survives lambda induction; stimulates DnaK and HscC ATPase[4] |
| EC number (for enzymes) |
|
| edit table |
Notes
Function
Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.
| Qualifier | GO ID | GO term name | Reference(s) | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005737 |
cytoplasm |
IDA: Inferred from Direct Assay |
C |
Seeded from EcoCyc 12.5 [6] |
complete | |||
| GO:0000774 |
adenyl-nucleotide exchange factor activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc [7] |
complete | |||
| GO:0005515 |
protein binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc [7] |
complete | |||
| GO:0005737 |
cytoplasm |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc 12.5 [6] |
complete | |||
| GO:0006457 |
protein folding |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc [7] |
complete | |||
| GO:0006950 |
response to stress |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc [7] |
complete | |||
| GO:0030189 |
chaperone activator activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc [7] |
complete | |||
| GO:0042803 |
protein homodimerization activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc [7] |
complete | |||
| GO:0051087 |
chaperone binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc [7] |
complete | |||
| GO:0000910 |
cytokinesis |
P |
Seeded from EcoCyc 11.1[3]. |
required fields missing | ||||
| GO:0009408 |
response to heat |
IEP: Inferred from Expression Pattern |
P |
complete | ||||
| edit table |
Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.
| Partner Type | Partner | Notes | References | Evidence |
|---|---|---|---|---|
|
Protein |
Subunits of DnaJ/DnaK/GrpE |
could be indirect | ||
|
Protein |
Experiment(s):EBI-881166 | |||
|
Protein |
Experiment(s):EBI-881166 | |||
|
Protein |
Experiment(s):EBI-888219 | |||
|
Protein |
Experiment(s):EBI-888219 | |||
|
Protein |
Experiment(s):EBI-888219 | |||
|
Protein |
Experiment(s):EBI-888219 | |||
|
Protein |
Experiment(s):EBI-888219 | |||
|
Protein |
Experiment(s):EBI-888219 | |||
|
Protein |
Experiment(s):EBI-888219 | |||
|
Protein |
Experiment(s):EBI-888219 | |||
|
Protein |
Experiment(s):EBI-888219 | |||
|
Protein |
Experiment(s):EBI-888219 | |||
|
Protein |
Experiment(s):EBI-888219 | |||
|
Protein |
Experiment(s):EBI-888219 | |||
|
Protein |
Experiment(s):EBI-888219 | |||
|
Protein |
Experiment(s):EBI-888219 | |||
|
Protein |
Experiment(s):EBI-888219 | |||
|
Protein |
Experiment(s):EBI-888219 | |||
|
Protein |
Experiment(s):EBI-888219 | |||
|
Protein |
Experiment(s):EBI-1143469 | |||
|
Protein |
Experiment(s):EBI-1143469 | |||
|
Protein |
Experiment(s):EBI-1143469 | |||
|
Protein |
Experiment(s):EBI-1143469 | |||
|
Protein |
Experiment(s):EBI-1143469 | |||
|
Protein |
Experiment(s):EBI-1143469 | |||
|
Protein |
Experiment(s):EBI-1143469 | |||
|
Protein |
Experiment(s):EBI-1143469 | |||
|
Protein |
Experiment(s):EBI-1143469 | |||
|
Protein |
Experiment(s):EBI-1143469 | |||
|
Protein |
Experiment(s):EBI-1143469 | |||
|
Protein |
Experiment(s):EBI-1143469 | |||
|
Protein |
Experiment(s):EBI-1143469 | |||
|
Protein |
Experiment(s):EBI-1143469 | |||
|
Protein |
Experiment(s):EBI-1143469 | |||
|
Protein |
Experiment(s):EBI-1143469 | |||
|
Protein |
Experiment(s):EBI-1143469 | |||
|
Protein |
Experiment(s):EBI-1143469 | |||
|
Protein |
Experiment(s):EBI-1143469 | |||
|
Protein |
Experiment(s):EBI-1143469 | |||
|
Protein |
Experiment(s):EBI-1143469 | |||
|
Protein |
Experiment(s):EBI-1143469 | |||
|
Protein |
Experiment(s):EBI-1143469 | |||
|
Protein |
Experiment(s):EBI-1143469 | |||
| edit table |
Notes
Localization
See Help:Product_localization for how to add or edit information in this section of EcoliWiki.
| Compartment | Description | Evidence | Source | Notes |
|---|---|---|---|---|
| edit table |
Notes
Structure and Physical Properties
Physical Properties
See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.
| Sequence |
MSSKEQKTPE GQAPEEIIMD QHEEIEAVEP EASAEQVDPR DEKVANLEAQ LAEAQTRERD GILRVKAEME NLRRRTELDI EKAHKFALEK FINELLPVID SLDRALEVAD KANPDMSAMV EGIELTLKSM LDVVRKFGVE VIAETNVPLD PNVHQAIAMV ESDDVAPGNV LGIMQKGYTL NGRTIRAAMV TVAKAKA |
|---|---|
| Length |
197 |
| Mol. Wt |
21.797 kDa |
| pI |
4.6 (calculated) |
| Extinction coefficient |
1,490 (calc based on 1 Y, W, and C residues) |
| edit table |
|
See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.
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Structure
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Structure figures
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| Resource type | Source | Notes/Reference |
|---|---|---|
| edit table |
Notes
Accessions in Other Databases
See Help:Gene_accessions for help with entering information into the Gene Accessions table.
| Database | Accession | Notes |
|---|---|---|
|
| ||
| edit table |
Notes
Links
| Name | URL | Comments |
|---|---|---|
| edit table |
References
See Help:References for how to manage references in EcoliWiki.
- ↑ 1.0 1.1 1.2 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 3.2 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
- ↑ Lasserre JP et al. (2006) A complexomic study of Escherichia coli using two-dimensional blue native/SDS polyacrylamide gel electrophoresis. Electrophoresis 27: 3306-21 PubMed EcoliWiki page
- ↑ 6.0 6.1 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 7.0 7.1 7.2 7.3 7.4 7.5 7.6 EcoCyc (release 13.0; 2009) Keseler, IM et al. (2009) Nucleic Acids Res. 37(Database issue):D464-70
- ↑ Chuang SE & Blattner FR (1993) Characterization of twenty-six new heat shock genes of Escherichia coli. J Bacteriol 175: 5242-52 PubMed EcoliWiki page
- ↑ 9.00 9.01 9.02 9.03 9.04 9.05 9.06 9.07 9.08 9.09 9.10 9.11 9.12 9.13 9.14 9.15 9.16 9.17 9.18 Butland G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433: 531-7 PubMed EcoliWiki page
- ↑ 10.00 10.01 10.02 10.03 10.04 10.05 10.06 10.07 10.08 10.09 10.10 10.11 10.12 10.13 10.14 10.15 10.16 10.17 10.18 10.19 10.20 10.21 10.22 10.23 Arifuzzaman M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res 16: 686-91 PubMed EcoliWiki page

