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Standard Name


Gene Synonym(s)

ECK1089, b1103, JW1089, ycfF[1], ycfF

Product Desc.

purine nucleoside phosphoramidase[2][3]

Purine nucleoside phosphoramidase; aminoacyl-adenylate hydrolase; physological role unknown[4]

Product Synonyms(s)

purine nucleoside phosphoramidase[1], B1103[2][1], YcfF[2][1], HinT[2][1] , ECK1089, JW1089, ycfF, b1103

Function from GO
Knock-Out Phenotype

transcription unit(s): hinT[2]

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HinT hydrolyzes lysyl-AMP, an activity that may be involved in the regulation of translation or the scavanging of aminoacyl-adenylates (Chou, 2006). hinT is essential for growth under high salt conditions (Chou, 2005). HinT is a member of the HIT (histidine triad) family that contains Ap3A and Ap4A hydrolases. HinT is a low abundance protein.[4]


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  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.