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hypB:Quickview

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Standard Name

hypB

Gene Synonym(s)

ECK2722, b2727, JW2697, hydA, hydE, hydB[1], hydB

Product Desc.

accessory protein for nickel incorporation into hydrogenase isoenzymes[2][3]

Required for metallocenter assembly in Hydrogenases 1,2,3; guanine-nucleotide-binding protein; Ni donor for Hyd-3 large subunit; homodimeric[4]

Product Synonyms(s)

GTP hydrolase involved in nickel liganding into hydrogenases[1], B2727[2][1], HydB[2][1], HypB[2][1] , ECK2722, hydB, hydE, JW2697, b2727

Function from GO
Knock-Out Phenotype
Regulation/Expression

transcription unit(s): hypBCDE-fhlA[2], hypABCDE-fhlA[2], hypBCDE[2], hydBEF, hypABCDE[2], OP00209

Regulation/Activity
Quick Links

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Notes

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hypB mutants are pheotypically suppressed by added Ni. HypB has a low level GTPase activity.[4]



References

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  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.