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ilvC:Gene Product(s)
From EcoliWiki
| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| Nomenclature | Function | Interactions | Localization | Sequence | Domains | Structure | Resources | Accessions | Links | References | Suggestions |
Nomenclature
See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.
| Standard name |
IlvC |
|---|---|
| Synonyms |
ketol-acid reductoisomerase, NAD(P)-binding[1], B3774[2][1], IlvC[2][1] |
| Product description |
Ketol-acid reductoisomerase[3] |
| EC number (for enzymes) | |
| edit table |
Notes
Function
Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.
| Qualifier | GO ID | GO term name | Reference(s) | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004455 |
ketol-acid reductoisomerase activity |
IDA: Inferred from Direct Assay |
F |
Seeded from EcoCyc 12.5 [5] |
complete | |||
| GO:0005515 |
protein binding |
IPI: Inferred from Physical Interaction |
F |
Seeded from EcoCyc [7] |
complete | |||
| GO:0005829 |
cytosol |
IDA: Inferred from Direct Assay |
C |
Seeded from EcoCyc [7] |
complete | |||
| GO:0009097 |
isoleucine biosynthetic process |
IDA: Inferred from Direct Assay |
P |
Seeded from EcoCyc 12.5 [5] |
complete | |||
| GO:0009099 |
valine biosynthetic process |
IDA: Inferred from Direct Assay |
P |
Seeded from EcoCyc 12.5 [5] |
complete | |||
| GO:0004455 |
ketol-acid reductoisomerase activity |
IEA: Inferred from Electronic Annotation |
InterPro:IPR000506 |
F |
Seeded from EcoCyc 12.5 [5] |
complete | ||
| GO:0009097 |
isoleucine biosynthetic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc 12.5 [5] |
complete | |||
| GO:0009099 |
valine biosynthetic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc 12.5 [5] |
complete | |||
| GO:0050661 |
NADP or NADPH binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc [7] |
complete | |||
| GO:0005737 |
cytoplasm |
C |
Seeded from EcoCyc 11.1[9]. |
required fields missing | ||||
| GO:0003824 |
catalytic activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc [7] |
complete | |||
| GO:0005488 |
binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc [7] |
complete | |||
| GO:0008152 |
metabolic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc [7] |
complete | |||
| GO:0008652 |
amino acid biosynthetic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc [7] |
complete | |||
| GO:0009082 |
branched chain family amino acid biosynthetic process |
IEA: Inferred from Electronic Annotation |
InterPro:IPR000506 |
P |
Seeded from EcoCyc [7] |
complete | ||
| GO:0016491 |
oxidoreductase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc [7] |
complete | |||
| GO:0055114 |
oxidation reduction |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc [7] |
complete | |||
| edit table |
Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.
| Partner Type | Partner | Notes | References | Evidence |
|---|---|---|---|---|
|
Protein |
Experiment(s):EBI-1146665 | |||
| edit table |
Notes
Localization
See Help:Product_localization for how to add or edit information in this section of EcoliWiki.
| Compartment | Description | Evidence | Source | Notes |
|---|---|---|---|---|
|
cytoplasm |
| |||
| edit table |
Notes
Structure and Physical Properties
Physical Properties
See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.
| Sequence |
MANYFNTLNL RQQLAQLGKC RFMGRDEFAD GASYLQGKKV VIVGCGAQGL NQGLNMRDSG LDISYALRKE AIAEKRASWR KATENGFKVG TYEELIPQAD LVINLTPDKQ HSDVVRTVQP LMKDGAALGY SHGFNIVEVG EQIRKDITVV MVAPKCPGTE VREEYKRGFG VPTLIAVHPE NDPKGEGMAI AKAWAAATGG HRAGVLESSF VAEVKSDLMG EQTILCGMLQ AGSLLCFDKL VEEGTDPAYA EKLIQFGWET ITEALKQGGI TLMMDRLSNP AKLRAYALSE QLKEIMAPLF QKHMDDIISG EFSSGMMADW ANDDKKLLTW REETGKTAFE TAPQYEGKIG EQEYFDKGVL MIAMVKAGVE LAFETMVDSG IIEESAYYES LHELPLIANT IARKRLYEMN VVISDTAEYG NYLFSYACVP LLKPFMAELQ PGDLGKAIPE GAVDNGQLRD VNEAIRSHAI EQVGKKLRGY MTDMKRIAVA G |
|---|---|
| Length |
491 |
| Mol. Wt |
54.069 kDa |
| pI |
5.1 (calculated) |
| Extinction coefficient |
52,830 - 53,580 (calc based on 17 Y, 5 W, and 6 C residues) |
| edit table |
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See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.
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Structure
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Structure figures
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| Resource type | Source | Notes/Reference |
|---|---|---|
| edit table |
Notes
Accessions in Other Databases
See Help:Gene_accessions for help with entering information into the Gene Accessions table.
| Database | Accession | Notes |
|---|---|---|
|
| ||
| edit table |
Notes
Links
| Name | URL | Comments |
|---|---|---|
| edit table |
References
See Help:References for how to manage references in EcoliWiki.
- ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
- ↑ 4.0 4.1 4.2 Chunduru SK et al. (1989) Mechanism of ketol acid reductoisomerase--steady-state analysis and metal ion requirement. Biochemistry 28: 486-93 PubMed EcoliWiki page
- ↑ 5.0 5.1 5.2 5.3 5.4 5.5 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 6.0 6.1 Arifuzzaman M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res 16: 686-91 PubMed EcoliWiki page
- ↑ 7.0 7.1 7.2 7.3 7.4 7.5 7.6 7.7 7.8 7.9 EcoCyc (release 13.0; 2009) Keseler, IM et al. (2009) Nucleic Acids Res. 37(Database issue):D464-70
- ↑ Ratzkin B et al. (1972) Isoleucine and valine metabolism in Escherichia coli. 18. Induction of acetohydroxy acid isomeroreductase. J Bacteriol 112: 131-41 PubMed EcoliWiki page
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
