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waaA:Quickview

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Standard Name

waaA

Gene Synonym(s)

kdtA, ECK3623, b3633, JW3608[1][2], JW3608

Product Desc.

3-deoxy-D-manno-octulosonate(Kdo)-lipid A transferase[3]

Product Synonyms(s)

3-deoxy-D-manno-octulosonic-acid transferase (KDO transferase)[1], B3633[4][1], WaaA[4][1], KdtA[4][1] , ECK3623, JW3608, kdtA, b3633

Function from GO
Knock-Out Phenotype

lethal (see PMID:7499229[5])

Regulation/Expression

transcription unit(s): kdtA[4], kdtA-coaD[4], kdtAB, waaA-coaD

Regulation/Activity
Quick Links

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Notes

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WaaA adds 2 Kdo residues to lipid IVA. waaA is an essential gene. Mutagenesis eliminated ATG a codon 52 as a start codon (Belunis and Raetz, 1992).[3]



References

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  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  4. 4.0 4.1 4.2 4.3 4.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  5. Belunis, CJ et al. (1995) Inhibition of lipopolysaccharide biosynthesis and cell growth following inactivation of the kdtA gene in Escherichia coli. J. Biol. Chem. 270 27646-52 PubMed EcoliWiki page