E. coli is indeed the coolest thing on the planet - Carl Zimmer
leuB:Gene Product(s)
From EcoliWiki
| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| Nomenclature | Function | Interactions | Localization | Sequence | Domains | Structure | Resources | Accessions | Links | References | Suggestions |
Nomenclature
| Standard name |
LeuB product |
|---|---|
| Synonyms |
3-isopropylmalate dehydrogenase product[1], B0073 product[2][1], LeuB product[2][1] |
| Product description |
Component of ; 3-isopropylmalate dehydrogenase[2][3] |
| EC number (for enzymes) | |
| edit table |
See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.
Notes
Function
Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.
| Qualifier | GO ID | GO term name | Reference(s) | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003862 |
3-isopropylmalate dehydrogenase activity |
IDA: Inferred from Direct Assay |
F |
Seeded from EcoCyc 12.5 [5] |
complete | |||
| GO:0009098 |
leucine biosynthetic process |
IDA: Inferred from Direct Assay |
P |
Seeded from EcoCyc 12.5 [5] |
complete | |||
| GO:0000287 |
magnesium ion binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc 12.5 [5] |
complete | |||
| GO:0003862 |
3-isopropylmalate dehydrogenase activity |
IEA: Inferred from Electronic Annotation |
InterPro:IPR004429 |
F |
Seeded from EcoCyc 12.5 [5] |
complete | ||
| GO:0005737 |
cytoplasm |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc 12.5 [5] |
complete | |||
| GO:0009098 |
leucine biosynthetic process |
IEA: Inferred from Electronic Annotation |
InterPro:IPR004429 |
P |
Seeded from EcoCyc 12.5 [5] |
complete | ||
| GO:0030145 |
manganese ion binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc 12.5 [5] |
complete | |||
| GO:0046872 |
metal ion binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc 12.5 [5] |
complete | |||
| GO:0009098 |
leucine biosynthetic process |
IDA |
P |
Seeded from EcoCyc 11.1[3]. |
required fields missing | |||
| GO:0003862 |
3-isopropylmalate dehydrogenase activity |
IDA |
F |
Seeded from EcoCyc 11.1[3]. |
required fields missing | |||
| edit table |
Interactions
| Partner Type | Partner | Notes | References |
|---|---|---|---|
|
Protein |
Subunits of 3-isopropylmalate dehydrogenase |
could be indirect |
|
| edit table |
See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.
Notes
Localization
| Compartment | Description | Evidence | Notes |
|---|---|---|---|
| edit table |
See Help:Product_localization for how to add or edit information in this section of EcoliWiki.
Notes
Structure and Physical Properties
Physical Properties
| Sequence |
MMSKNYHIAV LPGDGIGPEV MTQALKVLDA VRNRFAMRIT TSHYDVGGAA IDNHGQPLPP ATVEGCEQAD AVLFGSVGGP KWEHLPPDQQ PERGALLPLR KHFKLFSNLR PAKLYQGLEA FCPLRADIAA NGFDILCVRE LTGGIYFGQP KGREGSGQYE KAFDTEVYHR FEIERIARIA FESARKRRHK VTSIDKANVL QSSILWREIV NEIATEYPDV ELAHMYIDNA TMQLIKDPSQ FDVLLCSNLF GDILSDECAM ITGSMGMLPS ASLNEQGFGL YEPAGGSAPD IAGKNIANPI AQILSLALLL RYSLDADDAA CAIERAINRA LEEGIRTGDL ARGAAAVSTD EMGDIIARYV AEGV |
|---|---|
| Mol. Wt |
39.52 kDa (calc) [2] |
| pI | |
| Extinction coefficient |
27390 - 28140 (calc based on 11 Y, 2 W, and 6 C residues) |
| edit table |
See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.
Domains/Motifs/Modification Sites
| Type | Residues | Description | Notes |
|---|---|---|---|
| edit table |
See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.
Structure
| Structures |
|
|---|---|
| Models |
View models at: |
| edit table |
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.
Notes
Gene Product Resources
| Resource type | Source | Notes/Reference |
|---|---|---|
| edit table |
See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.
Notes
Accessions in Other Databases
| Database | Accession | Notes |
|---|---|---|
|
| ||
| edit table |
See Help:Product_accessions for help entering or editing information in this section of EcoliWiki.
Notes
Links
| Name | URL | Comments |
|---|---|---|
| edit table |
See Help:Links_table for how to enter or edit information in this section of EcoliWiki.
References
See Help:References for how to manage references in EcoliWiki.
- ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 3.2 3.3 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 4.2 4.3 Wallon G et al. (1997) Purification, catalytic properties and thermostability of 3-isopropylmalate dehydrogenase from Escherichia coli. Biochim Biophys Acta 1337: 105-12 PubMed EcoliWiki page
- ↑ 5.0 5.1 5.2 5.3 5.4 5.5 5.6 5.7 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
Categories
