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References Suggestions

Standard Name


Gene Synonym(s)

ECK0869, b0878, JW0862, ybjY[1], ybjY

Product Desc.


Component of MacAB macrolide efflux transporter complex[2]; MacAB-TolC Macrolide Efflux Transport System[3]

Membrane fusion protein (MFP) for macrolide efflux; subunit of ABC-type, TolC-dependent transporter MacAB; signal anchor; periplasmic[4]

Product Synonyms(s)

macrolide transporter subunit, membrane fusion protein (MFP) component[1], B0878[2][1], YbjY[2][1], MacA[2][1] , ECK0869, JW0862, ybjY, b0878

Function from GO
Knock-Out Phenotype

transcription unit(s):

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OmpF consistently co-purifies with MacA; MacA stimulates MacB ATPase activity (Tikhonova, 2007).[4]


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  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.