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mazF:Gene Product(s)
From EcoliWiki
| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| Nomenclature | Function | Interactions | Localization | Sequence | Domains | Structure | Resources | Accessions | Links | References | Suggestions |
Nomenclature
| Standard name |
ChpA |
|---|---|
| Synonyms |
toxin of the ChpA-ChpR toxin-antitoxin system, endoribonuclease[1], B2782[2][1], MazF[2][1], ChpA[2][1], ChpAK[2][1] |
| Product description |
toxin of the MazEF "addiction module" that exhibits ribonuclease activity[2]; MazF toxin of the MazF-MazE toxin-antitoxin system that exhibits ribonuclease activity[3]; Component of ; MazF toxin of the MazF-MazE toxin-antitoxin system that exhibits ribonuclease activity[3]; MazE-MazF complex[3] |
| EC number (for enzymes) |
|
| edit table |
See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.
Notes
Function
Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.
| Qualifier | GO ID | GO term name | Reference(s) | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005515 |
protein binding |
IPI: Inferred from Physical Interaction |
F |
Seeded from EcoCyc 12.5 [5] |
complete | |||
| GO:0003677 |
DNA binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc 12.5 [5] |
complete | |||
| GO:0006401 |
RNA catabolic process |
P |
Seeded from EcoCyc 11.1[3]. |
required fields missing | ||||
| GO:0006979 |
response to oxidative stress |
P |
Seeded from EcoCyc 11.1[3]. |
required fields missing | ||||
| GO:0042493 |
response to drug |
P |
Seeded from EcoCyc 11.1[3]. |
required fields missing | ||||
| GO:0042594 |
response to starvation |
P |
Seeded from EcoCyc 11.1[3]. |
required fields missing | ||||
| GO:0006412 |
translation |
P |
Seeded from EcoCyc 11.1[3]. |
required fields missing | ||||
| GO:0016564 |
transcription repressor activity |
F |
Seeded from EcoCyc 10.6[2]. |
required fields missing | ||||
| GO:0009386 |
translational attenuation |
P |
Seeded from EcoCyc 11.1[3]. |
required fields missing | ||||
| edit table |
Interactions
| Partner Type | Partner | Notes | References |
|---|---|---|---|
|
Protein |
Subunits of MazF toxin of the MazF-MazE toxin-antitoxin system that exhibits ribonuclease activity |
could be indirect | |
|
Protein |
Subunits of MazE-MazF complex |
could be indirect |
|
| edit table |
See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.
Notes
Localization
| Compartment | Description | Evidence | Notes |
|---|---|---|---|
| edit table |
See Help:Product_localization for how to add or edit information in this section of EcoliWiki.
Notes
Structure and Physical Properties
Physical Properties
| Sequence |
MVSRYVPDMG DLIWVDFDPT KGSEQAGHRP AVVLSPFMYN NKTGMCLCVP CTTQSKGYPF EVVLSGQERD GVALADQVKS IAWRARGATK KGTVAPEELQ LIKAKINVLI G |
|---|---|
| Mol. Wt |
12.1 kDa (calc) [2] |
| pI | |
| Extinction coefficient |
15470 - 15845 (calc based on 3 Y, 2 W, and 3 C residues) |
| edit table |
See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.
Domains/Motifs/Modification Sites
| Type | Residues | Description | Notes |
|---|---|---|---|
| edit table |
See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.
Structure
| Structures |
|
|---|---|
| Models |
View models at: |
| edit table |
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.
Notes
Gene Product Resources
| Resource type | Source | Notes/Reference |
|---|---|---|
| edit table |
See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.
Notes
Accessions in Other Databases
| Database | Accession | Notes |
|---|---|---|
|
| ||
| edit table |
See Help:Product_accessions for help entering or editing information in this section of EcoliWiki.
Notes
Links
| Name | URL | Comments |
|---|---|---|
| edit table |
See Help:Links_table for how to enter or edit information in this section of EcoliWiki.
References
See Help:References for how to manage references in EcoliWiki.
- ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 3.8 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ Arifuzzaman M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res 16: 686-91 PubMed EcoliWiki page
- ↑ 5.0 5.1 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
Categories
Categories: GO:0005515 ! protein binding | GO:0003677 ! DNA binding | GO:0006401 ! RNA catabolic process | GO:0006979 ! response to oxidative stress | GO:0042493 ! response to drug | GO:0042594 ! response to starvation | GO:0006412 ! translation | GO:0016564 ! transcription repressor activity | GO:0009386 ! translational attenuation | Complex:MazF toxin of the MazF-MazE toxin-antitoxin system that exhibits ribonuclease activity | Complex:MazE-MazF complex | Products with structures in PDB | Proteins
