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Standard Name


Gene Synonym(s)

ECK4005, b4013, JW3973[1], JW3973

Product Desc.


Component of homoserine O-succinyltransferase[2][3]

Homoserine O-transsuccinylase; also called homoserine O-succinyltransferase[4]

Product Synonyms(s)

homoserine transsuccinylase[1], B4013[2][1], MetA[2][1] , ECK4005, JW3973, b4013

Function from GO
Knock-Out Phenotype

transcription unit(s): metA[2], OP00051

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MetA catalyzes the first step in methionine biosynthesis and is proteolytically unstable. Upregulated by GSNO in defined medium (aerobic).[4]


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  1. 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.