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metG:Gene Product(s)
From EcoliWiki
| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| Nomenclature | Function | Interactions | Localization | Sequence | Domains | Structure | Resources | Accessions | Links | References | Suggestions |
Nomenclature
| Standard name |
MetG |
|---|---|
| Synonyms |
methionyl-tRNA synthetase[1], B2114[2][1], MetG[2][1], MetRS[2][1] |
| Product description |
methionyl-tRNA synthetase[2][3]; Component of ; methionyl-tRNA synthetase[2][3] |
| EC number (for enzymes) | |
| edit table |
See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.
Notes
Function
Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.
| Qualifier | GO ID | GO term name | Reference(s) | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005515 |
protein binding |
IPI: Inferred from Physical Interaction |
F |
Seeded from EcoCyc 12.5 [5] |
complete | |||
| GO:0005624 |
membrane fraction |
IDA: Inferred from Direct Assay |
C |
Seeded from EcoCyc 12.5 [5] |
complete | |||
| GO:0000049 |
tRNA binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc 12.5 [5] |
complete | |||
| GO:0000166 |
nucleotide binding |
GO_REF:0000002 |
IEA: Inferred from Electronic Annotation |
InterPro:IPR001412 |
F |
Seeded from EcoCyc 12.5 [5] |
complete | |
| GO:0003723 |
RNA binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc 12.5 [5] |
complete | |||
| GO:0004812 |
aminoacyl-tRNA ligase activity |
IEA: Inferred from Electronic Annotation |
InterPro:IPR001412 |
F |
Seeded from EcoCyc 12.5 [5] |
complete | ||
| GO:0004825 |
methionine-tRNA ligase activity |
GO_REF:0000002 |
IEA: Inferred from Electronic Annotation |
InterPro:IPR002304 |
F |
Seeded from EcoCyc 12.5 [5] |
complete | |
| GO:0005524 |
ATP binding |
GO_REF:0000002 |
IEA: Inferred from Electronic Annotation |
InterPro:IPR001412 |
F |
Seeded from EcoCyc 12.5 [5] |
complete | |
| GO:0005737 |
cytoplasm |
GO_REF:0000002 |
IEA: Inferred from Electronic Annotation |
InterPro:IPR001412 |
C |
Seeded from EcoCyc 12.5 [5] |
complete | |
| GO:0006412 |
translation |
GO_REF:0000002 |
IEA: Inferred from Electronic Annotation |
InterPro:IPR001412 |
P |
Seeded from EcoCyc 12.5 [5] |
complete | |
| GO:0006418 |
tRNA aminoacylation for protein translation |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc 12.5 [5] |
complete | |||
| GO:0006431 |
methionyl-tRNA aminoacylation |
IEA: Inferred from Electronic Annotation |
InterPro:IPR002304 |
P |
Seeded from EcoCyc 12.5 [5] |
complete | ||
| GO:0008270 |
zinc ion binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc 12.5 [5] |
complete | |||
| GO:0016874 |
ligase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc 12.5 [5] |
complete | |||
| GO:0046872 |
metal ion binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc 12.5 [5] |
complete | |||
| edit table |
Interactions
| Partner Type | Partner | Notes | References |
|---|---|---|---|
|
Protein |
Subunits of methionyl-tRNA synthetase |
could be indirect |
|
| edit table |
See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.
Notes
Localization
| Compartment | Description | Evidence | Notes |
|---|---|---|---|
| edit table |
See Help:Product_localization for how to add or edit information in this section of EcoliWiki.
Notes
Structure and Physical Properties
Physical Properties
| Sequence |
MTQVAKKILV TCALPYANGS IHLGHMLEHI QADVWVRYQR MRGHEVNFIC ADDAHGTPIM LKAQQLGITP EQMIGEMSQE HQTDFAGFNI SYDNYHSTHS EENRQLSELI YSRLKENGFI KNRTISQLYD PEKGMFLPDR FVKGTCPKCK SPDQYGDNCE VCGATYSPTE LIEPKSVVSG ATPVMRDSEH FFFDLPSFSE MLQAWTRSGA LQEQVANKMQ EWFESGLQQW DISRDAPYFG FEIPNAPGKY FYVWLDAPIG YMGSFKNLCD KRGDSVSFDE YWKKDSTAEL YHFIGKDIVY FHSLFWPAML EGSNFRKPSN LFVHGYVTVN GAKMSKSRGT FIKASTWLNH FDADSLRYYY TAKLSSRIDD IDLNLEDFVQ RVNADIVNKV VNLASRNAGF INKRFDGVLA SELADPQLYK TFTDAAEVIG EAWESREFGK AVREIMALAD LANRYVDEQA PWVVAKQEGR DADLQAICSM GINLFRVLMT YLKPVLPKLT ERAEAFLNTE LTWDGIQQPL LGHKVNPFKA LYNRIDMRQV EALVEASKEE VKAAAAPVTG PLADDPIQET ITFDDFAKVD LRVALIENAE FVEGSDKLLR LTLDLGGEKR NVFSGIRSAY PDPQALIGRH TIMVANLAPR KMRFGISEGM VMAAGPGGKD IFLLSPDAGA KPGHQVK |
|---|---|
| Mol. Wt |
76.25 kDa (calc) [2] |
| pI | |
| Extinction coefficient |
96260 - 97260 (calc based on 24 Y, 11 W, and 8 C residues) |
| edit table |
See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.
Domains/Motifs/Modification Sites
| Type | Residues | Description | Notes |
|---|---|---|---|
|
Domain |
575 - 677 | ||
| edit table |
See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.
Structure
| Structures |
|
|---|---|
| Models |
View models at: |
| edit table |
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.
Notes
Gene Product Resources
| Resource type | Source | Notes/Reference |
|---|---|---|
| edit table |
See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.
Notes
Accessions in Other Databases
| Database | Accession | Notes |
|---|---|---|
|
| ||
| edit table |
See Help:Product_accessions for help entering or editing information in this section of EcoliWiki.
Notes
Links
| Name | URL | Comments |
|---|---|---|
| edit table |
See Help:Links_table for how to enter or edit information in this section of EcoliWiki.
References
See Help:References for how to manage references in EcoliWiki.
- ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ Arifuzzaman M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res 16: 686-91 PubMed EcoliWiki page
- ↑ 5.00 5.01 5.02 5.03 5.04 5.05 5.06 5.07 5.08 5.09 5.10 5.11 5.12 5.13 5.14 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ Lasserre JP et al. (2006) A complexomic study of Escherichia coli using two-dimensional blue native/SDS polyacrylamide gel electrophoresis. Electrophoresis 27: 3306-21 PubMed EcoliWiki page
Categories
Categories: GO:0005515 ! protein binding | GO:0005624 ! membrane fraction | GO:0000049 ! tRNA binding | GO:0000166 ! nucleotide binding | GO:0003723 ! RNA binding | GO:0004812 ! aminoacyl-tRNA ligase activity | GO:0004825 ! methionine-tRNA ligase activity | GO:0005524 ! ATP binding | GO:0005737 ! cytoplasm | GO:0006412 ! translation | GO:0006418 ! tRNA aminoacylation for protein translation | GO:0006431 ! methionyl-tRNA aminoacylation | GO:0008270 ! zinc ion binding | GO:0016874 ! ligase activity | GO:0046872 ! metal ion binding | Proteins | Complex:methionyl-tRNA synthetase | Products with structures in PDB
