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Standard Name


Gene Synonym(s)

ECK3930, b3938, JW3909[1], JW3909

Product Desc.

MetJ transcriptional repressor[2][3]

Methionine regulon repressor, SAM co-repressor; sulfoximine and methylmethionine sensitivity[4]

Product Synonyms(s)

DNA-binding transcriptional repressor, S-adenosylmethionine-binding[1], B3938[2][1], MetJ[2][1], repressor of all met genes but metF[2][1] , ECK3930, JW3909, b3938

Function from GO
Knock-Out Phenotype

transcription unit(s): metJ[2]

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Upregulated by GSNO in defined medium (aerobic). MetJ-SAM also represses the SAM biosynthesic enzymes.[4]


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  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.