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Standard Name


Gene Synonym(s)

ECK2809, b2813, JW2784, waaN, mlt, ygdM, G330[1][2]

Product Desc.

membrane-bound lytic murein transglycosylase A[2][3]

Membrane-bound lytic transglycosylase A, murein hydrolase; periplasmic OM-attached lipoprotein[4]

Product Synonyms(s)

membrane-bound lytic murein transglycosylase A[1], B2813[2][1], YgdM[2][1], Mlt[2][1], MltA[2][1] , ECK2809, JW2784, mlt, ygdM, b2813

Function from GO

Cellular Component

Molecular Function

Knock-Out Phenotype

transcription unit(s): mltA[2]

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MltA cleaves the glycosidic bonds between the N-acetylmuramic acid and N-acetylglucosamine residues in murein. Unlike Slt and MltB, MltA can use peptide-free glycan as substrate. First 20 aa are a type II signal peptide. MltA forms a complex with MrcB and MipA.[4]


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  1. 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.