mnmA:Gene Product(s) - EcoliWiki
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mnmA:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

Standard name

TrmU

Synonyms

tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase[1], B1133[2][1], YcfB[2][1], AsuE[2][1], TrmU[2][1], MnmA[2][1]

Product description

tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase[2][3]

EC number (for enzymes)
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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

QualifierGO IDGO term nameReference(s)Evidence Codewith/fromAspectNotesStatus
GO:0004808

tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity

GO_REF:0000002
GO_REF:0000003
GO_REF:0000020

IEA: Inferred from Electronic Annotation

InterPro:IPR004506
EC:2.1.1.61
HAMAP:MF_00144

F

Seeded from EcoCyc 12.5 [4]

complete

GO:0005737

cytoplasm

GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR004506
SP_KW:KW-0963

C

Seeded from EcoCyc 12.5 [4]

complete

GO:0006400

tRNA modification

GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_00144

P

Seeded from EcoCyc 12.5 [4]

complete

GO:0008033

tRNA processing

GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR004506
SP_KW:KW-0819

P

Seeded from EcoCyc 12.5 [4]

complete

GO:0008168

methyltransferase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0489

F

Seeded from EcoCyc 12.5 [4]

complete

GO:0016740

transferase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0808

F

Seeded from EcoCyc 12.5 [4]

complete

GO:0009451

RNA modification

P

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0006399

tRNA metabolic process

P

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0006412

translation

P

Seeded from EcoCyc 11.1[3].

required fields missing

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Interactions

Partner TypePartnerNotesReferences
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Notes

Localization

CompartmentDescriptionEvidenceNotes
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Notes

Structure and Physical Properties

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Physical Properties

Sequence

at EcoCyc

MIEYAALKFN VVSDPMSETA KKVIVGMSGG VDSSVSAWLL QQQGYQVEGL FMKNWEEDDG
EEYCTAAADL ADAQAVCDKL GIELHTVNFA AEYWDNVFEL FLAEYKAGRT PNPDILCNKE
IKFKAFLEFA AEDLGADYIA TGHYVRRADV DGKSRLLRGL DSNKDQSYFL YTLSHEQIAQ
SLFPVGELEK PQVRKIAEDL GLVTAKKKDS TGICFIGERK FREFLGRYLP AQPGKIITVD
GDEIGEHQGL MYHTLGQRKG LGIGGTKEGT EEPWYVVDKD VENNILVVAQ GHEHPRLMSV
GLIAQQLHWV DREPFTGTMR CTVKTRYRQT DIPCTVKALD DDRIEVIFDE PVAAVTPGQS
AVFYNGEVCL GGGIIEQRLP LPV
Mol. Wt

40.96 kDa (calc) [2]

pI
Extinction coefficient

48360 - 49235 (calc based on 14 Y, 5 W, and 7 C residues)

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Domains/Motifs/Modification Sites

TypeResiduesDescriptionNotes
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Structure

Structures
  • Representative Escherichia coli structure:
    2DER|A
    13-380 of 383 residues (E-value: 3.3e-201) (Percent Identity: 100.00)
  • Representative homolog:
    2HMA|A (Streptococcus pneumoniae)
    1-364 of 383 residues (E-value: 3.0e-113) (Percent Identity: 58.20)
  • View all other structures.
Models

View models at:

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Notes

Gene Product Resources

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Resource typeSourceNotes/Reference
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Notes

Accessions in Other Databases

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DatabaseAccessionNotes

EcoCyc (EcoliWiki Page)

EcoCyc:EG11344-MONOMER

UniProt (EcoliWiki Page)

UniProt:P25745

PFAM (EcoliWiki Page)

PFAM:PF03054

RefSeq (EcoliWiki Page)

RefSeq:NP_415651

ModBase (EcoliWiki Page)

ModBase:P25745


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Notes

Links

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NameURLComments
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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 3.2 3.3 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 4.2 4.3 4.4 4.5 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7


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