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mog:On One Page

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Quickview | Gene | Product(s) | Expression| Evolution | References |

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Standard Name

mog

Gene Synonym(s)

ECK0009, b0009, JW0008, bisD, chlG, mogA, yaaG[1]

Product Desc.

predicted molybdochelatase[2][3]

Molybdochelatase incorporating molybdenum into molybdopterin; chlorate resistance[4]

Product Synonyms(s)

predicted molybdochelatase[1], B0009[2][1], YaaG[2][1], MogA[2][1], ChlG[2][1], BisD[2][1], Mog[2][1]

Function from GO

Cellular Component

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): mog[2]

Regulation/Activity
Quick Links

DNA display    Protein display    Pubmed(mog)    Textpresso(mog)

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Notes

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Mog is homologous to gephyrin. HT_Cmplx36_Cyt: Mog+YniC.[4]



Gene

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Nomenclature

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See Help:Gene_nomenclature for help with entering information in the Gene Nomenclature table.

Standard name

mog

Mnemonic

Molybdenum

Synonyms

ECK0009, b0009, JW0008, bisD, chlG, mogA, yaaG[1]

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Notes

Location(s) and DNA Sequence

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See Help:Gene_location for help entering information in the Gene Location and DNA sequence table.

StrainMap locationGenome coordinatesGenome browsersSequence links

MG1655

0.2 minutes 

MG1655: 9306..9893
gbrowse_img.php?coord=9306..9893&genome=ecoli&name=MG1655&trackset=0&width=300&.png

REL606

NC_012967: 9304..9891
gbrowse_img.php?coord=9304..9891&genome=REL606&name=NC_012967&trackset=0&width=300&.png

W3110

 

W3110: 9306..9893
gbrowse_img.php?coord=9306..9893&genome=ecoli_W3110&name=W3110&trackset=0&width=300&.png

DH10B

DH10B: 9306..9893
gbrowse_img.php?coord=9306..9893&genome=ecoli_DH10B&name=DH10B&trackset=0&width=300&.png

BW2952

NC_012759: 9306..9893
gbrowse_img.php?coord=9306..9893&genome=BW2952&name=NC_012759&trackset=0&width=300&.png

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Notes

Sequence Features

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See Help:Gene_sequence_features for help in entering sequence features in EcoliWiki.

Feature typeLocationDescription
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Notes

Alleles and Phenotypes

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See Help:Gene_alleles for how to enter or edit alleles and phenotypes in EcoliWiki.

AlleleNt change(s)AA change(s)Phenotype: TypePhenotype: DescriptionReferenceAvailabilityComments

Δmog (Keio:JW0008)

deletion

deletion

PMID:16738554

Shigen
CGSC8339[5]

mogD49A

D49A

Loss of activity

seeded from UniProt:P0AF03

mogD82A

D82A

Loss of activity

seeded from UniProt:P0AF03

mog-6

CGSC:6248

mog-21

CGSC:74592

mog-34

CGSC:74712

Δmog-729::kan

PMID:16738554

CGSC:101924


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Notes

Genetic Resources

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See Help:Gene_resources for help entering information into the Genetic Resources table.

ResourceResource TypeSourceNotes/Reference

JW0008

Plasmid clone

Shigen

PMID:16769691

Status:Clone OK

Primer 1:GCCAATACTTTACGTATTGGCTT

Primer 2:CCTTCGCTAACGTCGCGTCTTGC

thrA34::Tn10

Linked marker

CAG18442 = CGSC7320[5]

est. P1 cotransduction: 73% [6]
Synonyms:thr-34::Tn10

carB96::Tn10

Linked marker

CAG12093 = CGSC7322[5]

est. P1 cotransduction: 42% [6]
Synonyms:car-96::Tn10

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

DatabaseAccessionNotes

EcoCyc (EcoliWiki Page)

EcoCyc:EG11511

EchoBASE (EcoliWiki Page)

EchoBASE:EB1473

EcoliGenExpDB (EcoliWiki Page)

EcoliGenExpDB:b0009

ECOL199310CYC (EcoliWiki Page)

ECOL199310CYC:C0013

EcoGene (EcoliWiki Page)

EcoGene:EG11511

ECOO157CYC (EcoliWiki Page)

ECOO157CYC:MOG

CGSC (EcoliWiki Page)

CGSC:917

ASAP (EcoliWikiPage)

ASAP:ABE-0000030


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Notes

Links

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Product(s)

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Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

Mog

Synonyms

predicted molybdochelatase[1], B0009[2][1], YaaG[2][1], MogA[2][1], ChlG[2][1], BisD[2][1], Mog[2][1]

Product description

predicted molybdochelatase[2][3]

Molybdochelatase incorporating molybdenum into molybdopterin; chlorate resistance[4]

EC number (for enzymes)


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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

QualifierGO IDGO term nameReference(s)Evidence Codewith/fromAspectNotesStatus

GO:0005737

cytoplasm

PMID:16858726

IDA: Inferred from Direct Assay

C

Seeded from EcoCyc [7]

complete

GO:0006777

Mo-molybdopterin cofactor biosynthetic process

GO_REF:0000002
GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR001453
InterPro:IPR008284
SP_KW:KW-0501

P

Seeded from EcoCyc [7]

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner TypePartnerNotesReferencesEvidence

Protein

narX

PMID:16606699

Experiment(s):EBI-1135312

Protein

aceK

PMID:16606699

Experiment(s):EBI-1135312

Protein

gyrA

PMID:15690043

Experiment(s):EBI-888576

Protein

dnaK

PMID:15690043

Experiment(s):EBI-888576

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

CompartmentDescriptionEvidenceSourceNotes
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Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Sequence

at EcoCyc 

MNTLRIGLVS ISDRASSGVY QDKGIPALEE WLTSALTTPF ELETRLIPDE QAIIEQTLCE
LVDEMSCHLV LTTGGTGPAR RDVTPDATLA VADREMPGFG EQMRQISLHF VPTAILSRQV
GVIRKQALIL NLPGQPKSIK ETLEGVKDAE GNVVVHGIFA SVPYCIQLLE GPYVETAPEV
VAAFRPKSAR RDVSE
Length

195

Mol. Wt

21.221 kDa

pI

4.6 (calculated)

Extinction coefficient

9,970 - 10,345 (calc based on 3 Y, 1 W, and 3 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

TypeResiduesDescriptionNotesReferences
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Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures
Models

View models at:

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Structure figures

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource typeSourceNotes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

DatabaseAccessionNotes

EcoCyc (EcoliWiki Page)

EcoCyc:EG11511-MONOMER

SwissModel (EcoliWiki Page)

SwissModel:P0AF03

UniProt (EcoliWiki Page)

UniProt:P0AF03

PFAM (EcoliWiki Page)

PFAM:PF00994

RefSeq (EcoliWiki Page)

RefSeq:NP_414550


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Notes

Links

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Expression

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Overview

This is a placeholder for a summary statement on how expression of this gene product is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.


Cellular Levels

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See Help:Cellular levels

MoleculeOrganism or StrainCellular levelUnitsMediumTemperature °COther (e.g. anaerobic)Growth rateAssay usedNotesReference(s)
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Notes

Transcription and Transcriptional Regulation

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See Help:Expression_transcription for help entering or editing information in this section of EcoliWiki.

Transcription unit(s)

mog

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Figure courtesy of RegulonDB

Notes

This is a placeholder for a summary statement about how transcription of this gene is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.

Translation and Regulation of Translation

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gbrowse_img.php?coord=9286..9326&genome=ecoli&name=MG1655&trackset=Gene+DNA_+Protein&width=400&figure=Nterm&.png
This picture shows the sequence around the N-terminus.

Notes

This is a placeholder for a summary statement about how translation of this gene product is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.

Turnover and Regulation of Turnover

Notes

This is a placeholder for a summary statement about turnover of this gene product. You can help EcoliWiki by becoming a user and writing/editing this statement.

Experimental

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Mutations Affecting Expression See Help:Expression_mutations for help entering or editing information in this section of EcoliWiki.

Allele NameMutationPhenotypeReference
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Expression Studies See Help:Expression_studies for help entering or editing information in this section of EcoliWiki.

TypeReferenceNotes

microarray

GEO Profiles:b0009 (EcoliWiki Page)

NCBI GEO profiles for mog

microarray

GenExpDB:b0009 (EcoliWiki Page)

Summary of data for mog from multiple microarray studies

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Expression Resources See Help:Expression_resources for help entering or editing information in this section of EcoliWiki.

Resource NameResource TypeDescriptionSourceNotes

GFP Fusion

Intergenic region (9121..9336) fused to gfpmut2.

OpenBioSystems

GFP fusion described in Zaslaver, et al.
Plate:109-AZ07; Well:F8[8]

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Notes

Accessions Related to mog Expression

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

DatabaseAccessionNotes

EcoCyc (EcoliWiki Page)

EcoCyc:EG11511

EchoBASE (EcoliWiki Page)

EchoBASE:EB1473

EcoliGenExpDB (EcoliWiki Page)

EcoliGenExpDB:b0009

EcoGene (EcoliWiki Page)

EcoGene:EG11511


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Notes

Links

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Evolution

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Homologs in Other Organisms

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See Help:Evolution_homologs for help entering or editing information in this section of EcoliWiki.

OrganismHomologs (Statistics)Comments

Caenorhabditis briggsae

  • WBGene00038247 (score: 1.000; bootstrap: 100%)

From Inparanoid:20070104

Caenorhabditis elegans

  • WBGene00003385 (score: 1.000; bootstrap: 100%)

From Inparanoid:20070104

Shigella flexneri

MOG

From SHIGELLACYC

E. coli O157

MOG

From ECOO157CYC

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Do-It-Yourself Web Tools

Notes

Families

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

DatabaseAccessionNotes

PFAM (EcoliWiki Page)

PFAM:PF00994


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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 1.14 1.15 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 2.12 2.13 2.14 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 4.2 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.0 5.1 5.2 CGSC: The Coli Genetics Stock Center
  6. ↑ 6.0 6.1 The Tn10 insertion sites determined by Nichols et al. 1998 (PMID:9829956) were reannotated by alignment with E. coli K-12 genome sequence (GenBank accession NC_000913). P1 contransduction frequencies were calculated using the formula of Wu (PMID:5338813).
  7. ↑ 7.0 7.1 EcoCyc (release 13.0; 2009) Keseler, IM et al. (2009) Nucleic Acids Res. 37(Database issue):D464-70
  8. ↑ Zaslaver A et al. (2006) A comprehensive library of fluorescent transcriptional reporters for Escherichia coli. Nat Methods 3: 623-8 PubMed EcoliWiki page

Categories

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