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rsmH:Quickview

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References Suggestions

Standard Name

rsmH

Gene Synonym(s)

ECK0083, b0082, JW0080, yabC, orfB, mraW[1][2], mraW

Product Desc.

S-adenosyl-dependent methyltransferase[2][3]

SAM-dependent protein methyltransferase, membrane-associated; cellular function unknown, expressed gene in dcw gene cluster; non-essential[4]

Product Synonyms(s)

S-adenosyl-dependent methyltransferase activity on membrane-located substrates[1], B0082[2][1], YabC[2][1], RsmH[2][1], OrfB[2][1] , ECK0083, JW0080, mraW, yabC, b0082

Function from GO

Molecular Function

Cellular Component

Biological Process

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): mraZW-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ[2]

Regulation/Activity
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Notes

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At least four groups have deleted mraW(yabC): Carrion(1999) found it to be essential for growth; Arigoni(1998) found a reduced growth rate; Dassain(1999) and Merlin(2002) found that the deletion strain grew normally. A possible explanation is that the Carrion et al. mutation might be polar on a downstream essential gene. But this defect would have to be suppressible by MraW overexpression. Carrion(1999) found some protein starting with the second Met which might represent an alternative initiation site. Limiting MAP, when MraW is overproduced, is probably not the explanation since MM- is not a MAP substrate.[4]



References

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  1. 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.