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ompT:Gene

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Nomenclature Location(s) and DNA Sequence Alleles and Phenotypes Genetic Resources Accessions Links References Suggestions

Nomenclature

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See Help:Gene_nomenclature for help with entering information in the Gene Nomenclature table.

Standard name

ompT

Mnemonic

Outer membrane protein

Synonyms

ECK0557, b0565, JW0554[1]

Notes

Location(s) and DNA Sequence

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See Help:Gene_location for help entering information in the Gene Location and DNA sequence table.

StrainMap locationGenome coordinatesGenome browsersSequence links

MG1655

12.58 minutes 

MG1655: 584856..583903
gbrowse_img.php?coord=583903..584856&genome=ecoli&name=MG1655&trackset=0&width=300&.png

REL606

NC_012967: 560984..560031
gbrowse_img.php?coord=560031..560984&genome=REL606&name=NC_012967&trackset=0&width=300&.png

W3110

 

W3110: 584856..583903
gbrowse_img.php?coord=583903..584856&genome=ecoli_W3110&name=W3110&trackset=0&width=300&.png

DH10B

DH10B: 524188..523235
gbrowse_img.php?coord=523235..524188&genome=ecoli_DH10B&name=DH10B&trackset=0&width=300&.png

DH10B

DH10B: 637448..636495
gbrowse_img.php?coord=636495..637448&genome=ecoli_DH10B&name=DH10B&trackset=0&width=300&.png

BW2952

NC_012759: 486663..487616
gbrowse_img.php?coord=486663..487616&genome=BW2952&name=NC_012759&trackset=0&width=300&.png

Notes

Sequence Features

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See Help:Gene_sequence_features for help in entering sequence features in EcoliWiki.

Feature typeLocationDescription

Notes

Alleles and Phenotypes

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See Help:Gene_alleles for how to enter or edit alleles and phenotypes in EcoliWiki.

AlleleNt change(s)AA change(s)Phenotype: TypePhenotype: DescriptionReferenceAvailabilityComments

ΔompT (Keio:JW0554)

deletion

deletion

PMID:16738554[2]

Shigen
CGSC8680[3]

ompTD103A

D103A

Loss of activity

seeded from UniProt:P09169

ompTD105A

D105A

Loss of activity

seeded from UniProt:P09169

ompTD230A

D230A

Loss of activity

seeded from UniProt:P09169

ompTGK236KG

GK236KG

70% of wild-type enzymatic activity

seeded from UniProt:P09169

ompTK237T

K237T

40% of wild-type enzymatic activity

seeded from UniProt:P09169

ompTR238L

R238L

Loss of activity

seeded from UniProt:P09169

ΔompT

deletion

deletion

lack ompT protease activity. lack the ability to cleave between specific paired basic amino acids

PMID:17880914[4]

ΔompT504

CGSC:28510

ompT1000::kan

CGSC:30156

ΔompT774::kan

PMID:16738554[2]

CGSC:102186


Notes

Genetic Resources

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See Help:Gene_resources for help entering information into the Genetic Resources table.

ResourceResource TypeSourceNotes/Reference

JW0554

Plasmid clone

Shigen

PMID:16769691[5]

Status:Clone OK

Primer 1:GCCCGGGCGAAACTTCTGGGAAT

Primer 2:CCAAATGTGTACTTAAGACCAGC

purK79::Tn10

Linked marker

CAG12171 = CGSC7342[3]

est. P1 cotransduction: 28% [6]
Synonyms:purE79::Tn10

dsbG601::Tn10

Linked marker

CAG12149 = CGSC7346[3]

est. P1 cotransduction: 9% [6]
Synonyms:zbd-601::Tn10, zbe-601::Tn10

Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

DatabaseAccessionNotes

EcoCyc (EcoliWiki Page)

EcoCyc:EG10673

EchoBASE (EcoliWiki Page)

EchoBASE:EB0667

EcoliGenExpDB (EcoliWiki Page)

EcoliGenExpDB:b0565

ECOL199310CYC (EcoliWiki Page)

ECOL199310CYC:C0652

EcoGene (EcoliWiki Page)

EcoGene:EG10673

ECOO157CYC (EcoliWiki Page)

ECOO157CYC:Z1931

CGSC (EcoliWiki Page)

CGSC:4984

ASAP (EcoliWikiPage)

ASAP:ABE-0001931


Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 Baba T et al. (2006) Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection. Mol Syst Biol 2: 2006.0008 PubMed EcoliWiki page
  3. 3.0 3.1 3.2 CGSC: The Coli Genetics Stock Center
  4. Bishop RE (2007) Structural biology of membrane-intrinsic beta-barrel enzymes: Sentinels of the bacterial outer membrane. Biochim Biophys Acta PubMed EcoliWiki page
  5. Kitagawa M et al. (2005) Complete set of ORF clones of Escherichia coli ASKA library (A Complete Set of E. coli K-12 ORF Archive): Unique Resources for Biological Research. DNA Res 12: 291-9 PubMed EcoliWiki page
  6. 6.0 6.1 The Tn10 insertion sites determined by Nichols et al. 1998 (PMID:9829956) were reannotated by alignment with E. coli K-12 genome sequence (GenBank accession NC_000913). P1 contransduction frequencies were calculated using the formula of Wu (PMID:5338813).

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